Heart:BAV患者更易出现颅内动脉瘤

2017-09-18 MedSci MedSci原创

二叶主动脉瓣(BAV)是一种常见的先天性心脏病,长期不治疗可引起动脉瘤,包括颅内动脉瘤。近日,在国际心血管权威杂志《Heart》上发表了一篇旨在评估BAV患者颅内动脉瘤的发生率和预后的临床研究。本研究纳入了1994年至2013年在梅奥诊所行头颅磁共振的BAV患者,并回顾分析其临床资料。最终共纳入678名患者,平均年龄是57±13岁,男性占71%(480名),平均随访时间是10±3年。结果表明,有1

二叶主动脉瓣(BAV)是一种常见的先天性心脏病,长期不治疗可引起动脉瘤,包括颅内动脉瘤。近日,在国际心血管权威杂志《Heart》上发表了一篇旨在评估BAV患者颅内动脉瘤的发生率和预后的临床研究。

本研究纳入了1994年至2013年在梅奥诊所行头颅磁共振的BAV患者,并回顾分析其临床资料。最终共纳入678名患者,平均年龄是57±13岁,男性占71%(480名),平均随访时间是10±3年。结果表明,有154名患者出现有主动脉缩窄(COA),有52名患者共出现59例颅内动脉瘤(7.7%),主动脉缩窄患者中有20名患者存在颅内动脉瘤(12.9%),无主动脉缩窄患者中有32名出现颅内动脉瘤(5.7%)(p<0.001)。在没有COA的患者中,女性和左右腱索融合是颅内动脉瘤发生的危险因素(HR 1.76, CI 1.31 - 2.68, p=0.03)。在52名出现有颅内动脉瘤的患者中,3名患者动脉瘤有扩大(6%),2名患者出现动脉瘤破裂(4%),4名患者接受了弹簧圈栓塞治疗(8%),对于626名没有颅内动脉瘤的患者,随访期间也没有出现新发的颅内动脉瘤。

研究结果表明,二叶主动脉瓣患者更易出现颅内动脉瘤,并且主动脉缩窄、左右腱索融合和女性性别可能是颅内动脉瘤的高危因素。

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    2017-09-20 zhaojie88
  2. [GetPortalCommentsPageByObjectIdResponse(id=1356508, encodeId=4da3135650847, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562695, encodeId=797e1562695c4, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245631, encodeId=ef0c245631be, content=感谢小编为williamhill asia 准备了如此丰盛的精神大餐.同时也向作者致谢!认真学习了.点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb131638261, createdName=lietome24, createdTime=Tue Sep 19 09:23:27 CST 2017, time=2017-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245392, encodeId=bb662453927d, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Sep 18 18:50:51 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245359, encodeId=18b42453597d, content=控制血压.避免劳累激动, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Sep 18 16:47:33 CST 2017, time=2017-09-18, status=1, ipAttribution=)]
    2017-09-20 slcumt
  3. [GetPortalCommentsPageByObjectIdResponse(id=1356508, encodeId=4da3135650847, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562695, encodeId=797e1562695c4, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245631, encodeId=ef0c245631be, content=感谢小编为williamhill asia 准备了如此丰盛的精神大餐.同时也向作者致谢!认真学习了.点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb131638261, createdName=lietome24, createdTime=Tue Sep 19 09:23:27 CST 2017, time=2017-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245392, encodeId=bb662453927d, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Sep 18 18:50:51 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245359, encodeId=18b42453597d, content=控制血压.避免劳累激动, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Sep 18 16:47:33 CST 2017, time=2017-09-18, status=1, ipAttribution=)]
    2017-09-19 lietome24

    感谢小编为williamhill asia 准备了如此丰盛的精神大餐.同时也向作者致谢!认真学习了.点赞!

    0

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    2017-09-18 tanxingdoctor

    学习啦!谢谢分享!

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1356508, encodeId=4da3135650847, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562695, encodeId=797e1562695c4, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Sep 20 06:37:00 CST 2017, time=2017-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245631, encodeId=ef0c245631be, content=感谢小编为williamhill asia 准备了如此丰盛的精神大餐.同时也向作者致谢!认真学习了.点赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eb131638261, createdName=lietome24, createdTime=Tue Sep 19 09:23:27 CST 2017, time=2017-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245392, encodeId=bb662453927d, content=学习啦!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Sep 18 18:50:51 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=245359, encodeId=18b42453597d, content=控制血压.避免劳累激动, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Sep 18 16:47:33 CST 2017, time=2017-09-18, status=1, ipAttribution=)]
    2017-09-18 楠博One

    控制血压.避免劳累激动

    0

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