J Cosmet Dermatol:皮下分离术联合透明质酸或聚乳酸线可更好的改善痤疮疤痕

2022-08-15 MedSci原创 MedSci原创

痤疮疤痕是皮肤科医生在日常工作中面临的一个非常常见的皮肤问题,也是造成患者社会心理困扰的最常见的美容问题之一。

痤疮疤痕是皮肤科医生在日常工作中面临的一个非常常见的皮肤问题,也是造成患者社会心理困扰的最常见的美容问题之一。研究表明,痤疮疤痕可能是由多种因素的相互作用造成的,包括炎症、细胞外基质的降解和异常肉芽组织的形成。皮下分离术是最常见的治疗技术之一,是采用斜面的皮下注射针进入疤痕组织下,切断纤维带,它可以对萎缩性痤疮瘢痕产生良好的效果,无论是单独使用还是与其他方式结合使用。近日,发表于J Cosmet Dermatol的一项研究评估皮下分离术与交联透明质酸(HA)或聚乳酸(PLLA)线结合治疗萎缩性痤疮后疤痕的疗效。

共有40名萎缩性痤疮疤痕的男女患者接受了皮下分离术,间隔1个月,共3次。在最后一次亚切术后,患者被重新随机分为2组,每组在一侧脸部接受HA或线的治疗,另一侧脸部接受皮下分离术,作为对照。医生和患者进行了临床评估。获得照片和皮肤活检。随访时间为6个月。

结果显示,67.3%的患者在仅接受皮下分离术后取得了明显的临床改善,而在皮下分离术与HA或PLLA线结合的情况下,则分别有94.1%和82.4%的患者取得了明显的临床改善。与单独的皮下分离术相比,联合组的患者满意度更高(P < 0.0001)。联合治疗组的副作用是可容忍的和短暂的。

综上所述,该研究结果表明,与单独的皮下分离术相比,皮下分离术联合HA或PLLA线可以提供更高的痤疮疤痕的明显临床改善。

原始出处:

Howyda M Ebrahim, et al., A combined approach of subcision with either cross-linked hyaluronic acid or threads in the treatment of atrophic acne scars. J Cosmet Dermatol. 2022 Aug;21(8):3334-3342. doi: 10.1111/jocd.14675.  

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    2022-09-29 一闲
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    2023-02-18 tcm99hq
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    2022-08-16 HinsMax

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