JACC:欧洲感染性心内膜炎流行病学变化趋势的研究

2017-12-06 MedSci MedSci原创

目前,欧洲尚缺乏基于大样本研究的感染性心内膜炎(IE)流行病学的变化趋势。 本回顾性、基于人群的时间趋势研究纳入了2003年至2014年西班牙国家卫生系统记录的诊断为感染性心内膜炎的出院患者,对其发病率、流行病学资料和预后进行了全面详细的评估和分析。最终,共纳入16867名IE患者,男性占66.3%。IE的发病率从2003年的2.72/10万人年增至2014年的3.49/10万人年,这种增加

目前,欧洲尚缺乏基于大样本研究的感染性心内膜炎(IE)流行病学的变化趋势。 本回顾性、基于人群的时间趋势研究纳入了2003年至2014年西班牙国家卫生系统记录的诊断为感染性心内膜炎的出院患者,对其发病率、流行病学资料和预后进行了全面详细的评估和分析。最终,共纳入16867名IE患者,男性占66.3%。IE的发病率从2003年的2.72/10万人年增至2014年的3.49/10万人年,这种增加在老年患者中更为显著。其中,感染最多的微生物为葡萄球菌(28.7%),其次是链球菌感染(20.4%)和肠球菌(13.1%)。有23%的患者接受了心脏手术治疗,院内死亡率为20.4%。在观察期间,被诊断为心脏瓣膜疾病和糖尿病的患者逐渐增多,而静脉用药率逐渐减少,院内并发症和心脏手术并发症的发生率逐渐增多。此外,调整后的住院死亡率逐年下降(每年减少0.2%)。 研究结果显示,感染性心内膜炎在近十年的发病率明显增加,在老年人群中更显著,感染的微生物种群也有细微的变化,住院死亡率逐年下降。原始出处:Carmen A et al.The Evolving Nature of Infective Endocar

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    2018-01-13 hbwxf
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    2017-12-08 xugumin

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