PLos One:下呼吸道样本是否有助于重大心脏手术后机械通气患者金葡菌携带情况的评估?

2018-12-27 xiangting MedSci原创

在MHS患者中通过包括LRT样本在内的方法检测金葡菌定植情况的产出有限。

接受重大心脏手术(MHS)的患者中经常对金葡菌的定植情况进行评估。尽管手术前尝试去污,但很大比例的MHS患者在手术时仍被金葡菌定植。通过对鼻外区域进行取样可以改善鼻部采样。这项研究评估了处理下呼吸道(LRT)分泌物是否可以增强MHS后金葡菌的检测。

按照标准方案,在手术时或术后即刻获取所有研究患者的鼻拭子和LRT抽吸物。一个拭子用于微生物实验室的培养,另一个拭子用于Xpert SA鼻内完全测定。

根据研究人员对定植的定义(培养阳性和/或PCR阳性),115名患者中有31名(26.9%)在手术时被定植。其中,仅有3名患者的LRT样本呈阳性(占总人群的2.6%,携带者的9.7%)。其余28名患者要么鼻腔样本阳性,要么两个样本均阳性。

在MHS患者中通过包括LRT样本在内的方法检测金葡菌定植情况的产出有限,必须与实验室工作量和实验室人员需求相平衡。

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    2019-10-31 zhzhxiang
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    2018-12-29 zhmscau

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