J Hypertens:高血压和多种心血管危险因素会增加视网膜静脉阻塞的风险

2019-05-06 xing.T 网络

由此可见,心血管危险因素比RVO存在的其他危险因素更重要。增加任何一个额外的危险因素,RVO的风险增加约40%,增加任何一个额外的心血管危险因素风险增加70%。

虽然几种视网膜静脉阻塞(RVO)的危险因素是已知的,但在许多情况下,引发RVO的原因尚不清楚。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员旨在评估RVO患者中多种危险因素的相关性。

Gutenberg RVO研究是一项观察性病例对照研究,评估RVO参与者以及相同数量的匹配对照者的血栓形成、血管、眼科和药物相关危险因素。条件logistic回归分析来估计由于几个风险因素导致的RVO风险。

92例RVO患者中,46例(50%)患有中央性RVO,31例(33.7%)患有分支RVO,15例(16.3例)患有半RVO。全身性高血压与RVO相关[任何RVO:比值比(OR):1.81; 95%置信区间(CI):1.14-2.88; 分支RVO:OR:2.56; 95%CI:1.08-6.10]。最常见的危险因素组合是高血压伴血脂异常(92例中的33例,占35.9%)和高同型半胱氨酸血症以及高水平的因子VIII(92例中10例,占10.9%)。风险总和得分增加一个额外危险因素对应血管危险因素的OR为1.74(95%CI:1.31-2.32),血栓形成危险因素的OR为1.38(95%CI:1.04-1.82),RVO的危险因素总数的OR为1.43(95%CI:1.20-1.70)。 

由此可见,心血管危险因素比RVO存在的其他危险因素更重要。增加任何一个额外的危险因素,RVO的风险增加约40%,增加任何一个额外的心血管危险因素风险增加70%。 

原始出处:

Ponto, Katharina A.et al.Hypertension and multiple cardiovascular risk factors increase the risk for retinal vein occlusions results from the Gutenberg Retinal Vein Occlusion Study.Journal of Hypertension. 2019.https://journals.lww.com/jhypertension/Abstract/publishahead/Hypertension_and_multiple_cardiovascular_risk.97203.aspx

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beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331498, encodeId=2b4113314984b, content=<a href='/topic/show?id=afab51e831d' target=_blank style='color:#2F92EE;'>#心血管危险因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51783, encryptionId=afab51e831d, topicName=心血管危险因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581622, encodeId=ea25158162288, content=<a href='/topic/show?id=0f8e90830d9' target=_blank style='color:#2F92EE;'>#视网膜静脉阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90830, encryptionId=0f8e90830d9, topicName=视网膜静脉阻塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629784, encodeId=1dde1629e8442, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1696882, encodeId=d7c316968823d, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Thu Jan 02 11:33:00 CST 2020, time=2020-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727978, encodeId=da071e27978ad, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331498, encodeId=2b4113314984b, content=<a href='/topic/show?id=afab51e831d' target=_blank style='color:#2F92EE;'>#心血管危险因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51783, encryptionId=afab51e831d, topicName=心血管危险因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1581622, encodeId=ea25158162288, content=<a href='/topic/show?id=0f8e90830d9' target=_blank style='color:#2F92EE;'>#视网膜静脉阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90830, encryptionId=0f8e90830d9, topicName=视网膜静脉阻塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629784, encodeId=1dde1629e8442, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=)]
    2019-08-26 fusion
  6. [GetPortalCommentsPageByObjectIdResponse(id=1696882, encodeId=d7c316968823d, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Thu Jan 02 11:33:00 CST 2020, time=2020-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727978, encodeId=da071e27978ad, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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GetPortalCommentsPageByObjectIdResponse(id=1581622, encodeId=ea25158162288, content=<a href='/topic/show?id=0f8e90830d9' target=_blank style='color:#2F92EE;'>#视网膜静脉阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90830, encryptionId=0f8e90830d9, topicName=视网膜静脉阻塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629784, encodeId=1dde1629e8442, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=)]
    2019-05-08 zutt
  7. [GetPortalCommentsPageByObjectIdResponse(id=1696882, encodeId=d7c316968823d, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Thu Jan 02 11:33:00 CST 2020, time=2020-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1727978, encodeId=da071e27978ad, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Wed May 08 10:33:00 CST 2019, time=2019-05-08, status=1, ipAttribution=)]
  8. 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