Brit J Anaesth:硬膜外相关产时发热的预防或干预措施

2022-08-07 MedSci原创 MedSci原创

没有明确的证据支持对硬膜外相关的产时发热使用任何个人预防或治疗干预措施。进一步的研究应集中于了解硬膜外相关的产时发热发生的机制,以使随机对照试验能够采取可能的干预措施,以减少产时发热的发生率。

硬膜外相关的产时发热指接受硬膜外分娩镇痛的产妇在分娩期间的核心温度≥37.5℃或≥38℃。硬膜外相关的产时发热的发生率因研究而异,从1.6%到46%变化不等。硬膜外相关的产时发热对产妇和新生儿都有影响,但没有系统地评估预防策略。

近日,麻醉学领域权威杂志British Journal of Anaesthesia上发表了一篇研究文章,研究人员纳入了评估预防或治疗活产妇女硬膜外相关产时发热方法的随机对照试验,并检索了MEDLINE、EMBASE、CINAHL、Web of Science、CENTRAL等数据库。

两位作者独立地进行了研究选择。数据提取和质量评估由另一名作者完成。研究人员使用Cochrane偏倚风险2工具进行了分析,并采用DerSimonian和Laird随机效应模型对主要结局、产时发热发生率进行Meta分析,得出伴有95%可信区间(95%CI)的总风险比(RRs)。

研究人员纳入了34项研究的42项记录。减少硬膜外麻醉用药剂量的方法降低了硬膜外相关的产时发热发生率,但当6项有高偏倚风险的试验被移除时(7项试验;857名参与者;RR=0.83;95%可信区间为0.41-1.67)。与硬膜外镇痛相比,替代方法的镇痛和高剂量预防性全身类固醇降低了分娩时发热的风险。预防性服用扑热息痛治疗无效。

由此可见,没有明确的证据支持对硬膜外相关的产时发热使用任何个人预防或治疗干预措施。进一步的研究应集中于了解硬膜外相关的产时发热发生的机制,以使随机对照试验能够采取可能的干预措施,以减少产时发热的发生率。

原始出处:

Anna Cartledge.et al.Interventions for the prevention or treatment of epidural-related maternal fever: a systematic review and meta-analysis.British Journal of Anaesthesia.2022.https://www.bjanaesthesia.org/article/S0007-0912(22)00323-3/fulltext

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1937192, encodeId=e508193e192c6, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Tue Apr 11 02:59:27 CST 2023, time=2023-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633654, encodeId=d0641633654a0, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Tue Nov 01 08:59:27 CST 2022, time=2022-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634576, encodeId=ead916345e621, content=<a href='/topic/show?id=b6974881243' target=_blank style='color:#2F92EE;'>#干预措施#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48812, encryptionId=b6974881243, topicName=干预措施)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a51a22195904, createdName=xiaoyang_ambs, createdTime=Tue Sep 27 21:59:27 CST 2022, time=2022-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051832, encodeId=39f820518327f, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Aug 16 14:59:27 CST 2022, time=2022-08-16, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1937192, encodeId=e508193e192c6, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Tue Apr 11 02:59:27 CST 2023, time=2023-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633654, encodeId=d0641633654a0, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Tue Nov 01 08:59:27 CST 2022, time=2022-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634576, encodeId=ead916345e621, content=<a href='/topic/show?id=b6974881243' target=_blank style='color:#2F92EE;'>#干预措施#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48812, encryptionId=b6974881243, topicName=干预措施)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a51a22195904, createdName=xiaoyang_ambs, createdTime=Tue Sep 27 21:59:27 CST 2022, time=2022-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051832, encodeId=39f820518327f, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Aug 16 14:59:27 CST 2022, time=2022-08-16, status=1, ipAttribution=)]
    2022-11-01 AspirantSuo
  3. [GetPortalCommentsPageByObjectIdResponse(id=1937192, encodeId=e508193e192c6, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Tue Apr 11 02:59:27 CST 2023, time=2023-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633654, encodeId=d0641633654a0, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Tue Nov 01 08:59:27 CST 2022, time=2022-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634576, encodeId=ead916345e621, content=<a href='/topic/show?id=b6974881243' target=_blank style='color:#2F92EE;'>#干预措施#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48812, encryptionId=b6974881243, topicName=干预措施)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a51a22195904, createdName=xiaoyang_ambs, createdTime=Tue Sep 27 21:59:27 CST 2022, time=2022-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051832, encodeId=39f820518327f, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Aug 16 14:59:27 CST 2022, time=2022-08-16, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1937192, encodeId=e508193e192c6, content=<a href='/topic/show?id=c06ae363256' target=_blank style='color:#2F92EE;'>#硬膜外#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73632, encryptionId=c06ae363256, topicName=硬膜外)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Tue Apr 11 02:59:27 CST 2023, time=2023-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1633654, encodeId=d0641633654a0, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Tue Nov 01 08:59:27 CST 2022, time=2022-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1634576, encodeId=ead916345e621, content=<a href='/topic/show?id=b6974881243' target=_blank style='color:#2F92EE;'>#干预措施#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48812, encryptionId=b6974881243, topicName=干预措施)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a51a22195904, createdName=xiaoyang_ambs, createdTime=Tue Sep 27 21:59:27 CST 2022, time=2022-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051832, encodeId=39f820518327f, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Tue Aug 16 14:59:27 CST 2022, time=2022-08-16, status=1, ipAttribution=)]

相关威廉亚洲官网

NEJM:瑞德西韦治疗可预防Covid-19门诊患者病情进展

在Covid-19进展风险较高的非住院患者中,瑞德西韦治疗3天的安全性可接受,与安慰剂相比,住院或死亡风险降低了87%。

2021WHO威廉亚洲博彩公司 :猪肉绦虫病的预防和控制

2021年9月,世界卫生组织(WHO)发布了猪肉绦虫病的预防和控制威廉亚洲博彩公司 ,本文主要针对猪肉绦虫病的预防和控制提供指导建议。

超40万人研究:得了高血压,2型糖尿病风险翻倍?6大生活方式因素或最多可将风险降低79%!

Cardiovasc Diabetol:高血压患者健康生活方式(包括健康睡眠模式)与2型糖尿病发病的关系

糖尿病的管理与预防:世界糖尿病日

糖尿病是由于胰岛素抵抗或者胰岛素分泌不足引起的代谢性疾病。它的发生是遗传和环境因素共同作用的结果。

红斑狼疮也有“选人标准”,快看看你中了几条

正所谓,知己知彼百战不殆。了解红斑狼疮的特点,更有助于williamhill asia 患者正视这个疾病,不致于过度恐慌,更重要的是,williamhill asia 患者可以根据狼疮的这些特点做好预防,防止病情复发。

产后风和类风湿关节炎不得不说的亲戚关系,如何预防?

妇生产或流产后,如果出现身体疼痛、四肢关节疼痛、食欲不振、自汗盗汗等身体不适,请尽快到风湿免疫专科就诊,及时诊断,以免耽误病情。