Ophthal Plast Reconstr Surg:完善眼睑痉挛的美容性眼轮匝肌切除术:局部使用5-氟尿嘧啶和纤维蛋白粘合剂!

2017-09-05 cuiguizhong MedSci原创

美国密歇根大学眼科与视觉科学系的Stewart KJ近日在Ophthal Plast Reconstr Surg发表了他们团队近期的一项工作,他们对治疗难治性眼睑痉挛的眼轮匝肌切除术进行了完善。完善后的技术包括去除眼轮匝肌,使用纤维蛋白粘合剂(Tisseel)重新修复眼睑皱纹,并局部使用5-氟尿嘧啶来减少瘢痕,改善美学效果。

美国密歇根大学眼科与视觉科学系的Stewart KJ近日在Ophthal Plast Reconstr Surg发表了他们团队近期的一项工作,他们对治疗难治性眼睑痉挛的眼轮匝肌切除术进行了完善。完善后的技术包括去除眼轮匝肌,使用纤维蛋白粘合剂(Tisseel)重新修复眼睑皱纹,并局部使用5-氟尿嘧啶来减少瘢痕,改善美学效果。

他们回顾分析了2013年至2016年间接受双眼眼轮匝肌切除术的7例患者。研究的主要指标为术后肉毒杆菌毒素剂量,使用频率,治疗持续时间,睑裂闭合不全的数量,干眼症状的严重程度,患者满意度和术后功能恢复情况。

最终,他们发现,进行完善的美容肌肉切除术的患者,显着的降低了肉毒杆菌毒素使用量,术后并发症得到有效缓解。 7例患者中只有1例患者术后出现轻度干眼症状,这可以用人工泪液来减轻症状。所有患者对外貌美观和功能结果都表示满意。

因此,他们认为,完善后的美容肌肉切除术为眼睑痉挛患者提供了有效的治疗方法,具有良好的功能和美学效果。

原文出处:

Stewart, K.J., S.S. Joseph, and R.S. Douglas, An Aesthetic Orbicularis Oculi Myectomy Technique for Blepharospasm: Use of Topical 5-Fluorouracil and Fibrin Sealant. Ophthal Plast Reconstr Surg, 2017

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  5. 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  6. 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  7. 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GetPortalCommentsPageByObjectIdResponse(id=1977530, encodeId=a58a19e753002, content=<a href='/topic/show?id=d9e5130962f' target=_blank style='color:#2F92EE;'>#NST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13096, encryptionId=d9e5130962f, topicName=NST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Aug 22 04:12:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311748, encodeId=88381311e4801, content=<a href='/topic/show?id=624de11204a' target=_blank style='color:#2F92EE;'>#痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71120, encryptionId=624de11204a, topicName=痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7dc7399, createdName=apoenzyme, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405752, encodeId=99d91405e525e, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1684097, encodeId=a7cd168409e0d, content=<a href='/topic/show?id=bf59e2814cf' target=_blank style='color:#2F92EE;'>#眼睑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72814, encryptionId=bf59e2814cf, topicName=眼睑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d8928034409, createdName=zhangbaojun, createdTime=Sun Sep 10 17:12:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711184, encodeId=18111e11184db, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Mar 01 05:12:00 CST 2018, time=2018-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739378, encodeId=157f1e393787a, content=<a href='/topic/show?id=9abce2823b5' target=_blank style='color:#2F92EE;'>#眼睑痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72823, encryptionId=9abce2823b5, topicName=眼睑痉挛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71cc34532311, createdName=ms920641618706883, createdTime=Thu Dec 14 10:12:00 CST 2017, time=2017-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688856, encodeId=6ef51688856d7, content=<a href='/topic/show?id=1e74e993465' target=_blank style='color:#2F92EE;'>#美容#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79934, encryptionId=1e74e993465, topicName=美容)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c23128667605, createdName=12498adam49暂无昵称, createdTime=Sun May 13 16:12:00 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1997243, encodeId=a5e0199e243d9, content=<a href='/topic/show?id=cc04e727535' target=_blank style='color:#2F92EE;'>#纤维蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77275, encryptionId=cc04e727535, topicName=纤维蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ad8182, createdName=axin009, createdTime=Tue Dec 19 04:12:00 CST 2017, time=2017-12-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876939, encodeId=e8a418e693938, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Mar 06 22:12:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804497, encodeId=dc3d180449eb7, content=<a href='/topic/show?id=2ff7e72839d' target=_blank style='color:#2F92EE;'>#纤维蛋白粘合剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77283, encryptionId=2ff7e72839d, topicName=纤维蛋白粘合剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Sat Dec 02 13:12:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977530, encodeId=a58a19e753002, content=<a href='/topic/show?id=d9e5130962f' target=_blank style='color:#2F92EE;'>#NST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13096, encryptionId=d9e5130962f, topicName=NST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Aug 22 04:12:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311748, encodeId=88381311e4801, content=<a href='/topic/show?id=624de11204a' target=_blank style='color:#2F92EE;'>#痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71120, encryptionId=624de11204a, topicName=痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7dc7399, createdName=apoenzyme, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405752, encodeId=99d91405e525e, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=)]
    2018-08-22 drj2003
  9. [GetPortalCommentsPageByObjectIdResponse(id=1684097, encodeId=a7cd168409e0d, content=<a href='/topic/show?id=bf59e2814cf' target=_blank style='color:#2F92EE;'>#眼睑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72814, encryptionId=bf59e2814cf, topicName=眼睑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9d8928034409, createdName=zhangbaojun, createdTime=Sun Sep 10 17:12:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711184, encodeId=18111e11184db, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Thu Mar 01 05:12:00 CST 2018, time=2018-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1739378, encodeId=157f1e393787a, content=<a href='/topic/show?id=9abce2823b5' target=_blank style='color:#2F92EE;'>#眼睑痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72823, encryptionId=9abce2823b5, topicName=眼睑痉挛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71cc34532311, createdName=ms920641618706883, createdTime=Thu Dec 14 10:12:00 CST 2017, time=2017-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1688856, encodeId=6ef51688856d7, content=<a href='/topic/show?id=1e74e993465' target=_blank style='color:#2F92EE;'>#美容#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, 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style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Mar 06 22:12:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804497, encodeId=dc3d180449eb7, content=<a href='/topic/show?id=2ff7e72839d' target=_blank style='color:#2F92EE;'>#纤维蛋白粘合剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77283, encryptionId=2ff7e72839d, topicName=纤维蛋白粘合剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Sat Dec 02 13:12:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977530, encodeId=a58a19e753002, content=<a href='/topic/show?id=d9e5130962f' target=_blank style='color:#2F92EE;'>#NST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13096, encryptionId=d9e5130962f, topicName=NST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Aug 22 04:12:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311748, encodeId=88381311e4801, content=<a href='/topic/show?id=624de11204a' target=_blank style='color:#2F92EE;'>#痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71120, encryptionId=624de11204a, topicName=痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7dc7399, createdName=apoenzyme, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405752, encodeId=99d91405e525e, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=)]
    2017-09-07 apoenzyme
  10. 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style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Mar 06 22:12:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1804497, encodeId=dc3d180449eb7, content=<a href='/topic/show?id=2ff7e72839d' target=_blank style='color:#2F92EE;'>#纤维蛋白粘合剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77283, encryptionId=2ff7e72839d, topicName=纤维蛋白粘合剂)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dab8203, createdName=zsyan, createdTime=Sat Dec 02 13:12:00 CST 2017, time=2017-12-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977530, encodeId=a58a19e753002, content=<a href='/topic/show?id=d9e5130962f' target=_blank style='color:#2F92EE;'>#NST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13096, encryptionId=d9e5130962f, topicName=NST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80c5136, createdName=drj2003, createdTime=Wed Aug 22 04:12:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311748, encodeId=88381311e4801, content=<a href='/topic/show?id=624de11204a' target=_blank style='color:#2F92EE;'>#痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71120, encryptionId=624de11204a, topicName=痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7dc7399, createdName=apoenzyme, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1405752, encodeId=99d91405e525e, content=<a href='/topic/show?id=a5404e589d7' target=_blank style='color:#2F92EE;'>#局部#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=47589, encryptionId=a5404e589d7, topicName=局部)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d14c2562456, createdName=chg122, createdTime=Thu Sep 07 12:12:00 CST 2017, time=2017-09-07, status=1, ipAttribution=)]
    2017-09-07 chg122