MyndYou应用AI治疗阿尔兹海默症

2017-08-10 羊药师 新浪医药

阿尔兹海默症等神经退行性疾病已经成为药物研发的重灾区。几十年来药企在这一领域不断受挫也让情况更显恶劣。随着AI技术的兴起,阿尔兹海默症领域的疗法开发似乎出现了一丝曙光。最近一家名为MyndYou的公司希望利用AI技术结合诊断工具通过追踪患者语言模式变化的方法来确定阿尔兹海默症患者的病情发展。

阿尔兹海默症等神经退行性疾病已经成为药物研发的重灾区。几十年来药企在这一领域不断受挫也让情况更显恶劣。随着AI技术的兴起,阿尔兹海默症领域的疗法开发似乎出现了一丝曙光。最近一家名为MyndYou的公司希望利用AI技术结合诊断工具通过追踪患者语言模式变化的方法来确定阿尔兹海默症患者的病情发展。

目前MyndYou公司正在与麻省总医院合作对这一工具进行测试。该研究希望确定MyndYou公司的这一技术能够自动追踪阿尔兹海默症患者病情的微弱变化。公司表示,目前研究者缺乏关于阿尔兹海默症患者认知功能变化的相关数据,而要解决这一问题就要对患者的日常生活进行密切追踪。

原发进行性失语(PPA)是阿尔兹海默症常见症状之一,研究人员认为这一症状在早期能够被缓解。因此能够早期检测到患者的语言功能变化就显得尤为重要。

MyndYou公司的AI技术采用了独特分析方法分析与患者认知功能相关的多个参数,其中就包括了患者的语言习惯。在这一过程中,研究人员主要利用手机app来实现数据的收集。研究人员表示,公司在设计之初就认为可穿戴设备并不是数据采集的最好方式。一方面是因为部分患者会对这一方式产生抵触,另一方面是患者有时可能会忘记佩戴。而智能手机已经成为人们不可或缺的部分,患者在通话时的声音将会被app记录并传输至后台进行分析并最终实现对患者的日常监测。同时,这一app还可以记录患者的其他日常活动,如睡眠状况等。

MyndYou的这一研究思路反映了如今医药产业中精准治疗的研发潮流。公司希望这一工具能够帮助研究人员更准确确定阿尔兹海默症患者早期阶段认知功能的细微变化,从而更好帮助研究人员确定该疾病的早期信号。

阿尔兹海默症最早于1906年,由德国精神病学家和病理学家爱罗斯·阿尔兹海默首次发现,因此而得名;主要分为家族性阿尔兹海默症与阿尔兹海默老年痴呆症两种,其中又以后者较常见。阿尔兹海默症好发于65岁以上的老年人(约有6%发生率),但有4%~5%的患者会在65岁之前就发病,属于早发性阿尔兹海默症。在2010年,全球有将近2100万到3500万名阿尔兹海默症患者;而归因于阿尔兹海默症相关的死亡案例,大约有48.6万例。在发达国家中,阿尔兹海默症是相当耗费社会财政补助的疾病之一。

随着老龄化进程加快,中国老年群体规模将不断增加。如何对抗阿尔兹海默症也必将成为中国医药工作者面临的重大问题。

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  1. [GetPortalCommentsPageByObjectIdResponse(id=238737, encodeId=b6a0238e3716, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Aug 30 17:57:19 CST 2017, time=2017-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235152, encodeId=c7b9235152c9, content=讲解的非常好,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 19 19:13:56 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232934, encodeId=2f6523293432, content=不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 12 19:53:12 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402725, encodeId=bc751402e2508, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Sat Aug 12 07:10:00 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232201, encodeId=601c2322012e, content=随着老龄化进程加快,中国老年群体规模将不断增加。如何对抗阿尔兹海默症也必将成为中国医药工作者面临的重大问题。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Aug 10 17:02:45 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-30 虈亣靌

    不错的.学习了.谢谢分享!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=238737, encodeId=b6a0238e3716, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Aug 30 17:57:19 CST 2017, time=2017-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235152, encodeId=c7b9235152c9, content=讲解的非常好,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 19 19:13:56 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232934, encodeId=2f6523293432, content=不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 12 19:53:12 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402725, encodeId=bc751402e2508, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Sat Aug 12 07:10:00 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232201, encodeId=601c2322012e, content=随着老龄化进程加快,中国老年群体规模将不断增加。如何对抗阿尔兹海默症也必将成为中国医药工作者面临的重大问题。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Aug 10 17:02:45 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-19 虈亣靌

    讲解的非常好,值得学习

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=238737, encodeId=b6a0238e3716, content=不错的.学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Aug 30 17:57:19 CST 2017, time=2017-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235152, encodeId=c7b9235152c9, content=讲解的非常好,值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 19 19:13:56 CST 2017, time=2017-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232934, encodeId=2f6523293432, content=不错的,学习了!谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Aug 12 19:53:12 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402725, encodeId=bc751402e2508, content=<a href='/topic/show?id=60ca9e761ce' target=_blank style='color:#2F92EE;'>#阿尔兹海默#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97761, encryptionId=60ca9e761ce, topicName=阿尔兹海默)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=be952422716, createdName=habb, createdTime=Sat Aug 12 07:10:00 CST 2017, time=2017-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=232201, encodeId=601c2322012e, content=随着老龄化进程加快,中国老年群体规模将不断增加。如何对抗阿尔兹海默症也必将成为中国医药工作者面临的重大问题。, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Thu Aug 10 17:02:45 CST 2017, time=2017-08-10, status=1, ipAttribution=)]
    2017-08-12 虈亣靌

    不错的,学习了!谢谢分享!

    0

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    2017-08-10 有备才能无患

    随着老龄化进程加快,中国老年群体规模将不断增加。如何对抗阿尔兹海默症也必将成为中国医药工作者面临的重大问题。

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