Neurology:1例与卒中后延迟钆渗漏相关的血管周围和蛛网膜下腔液体衰减反转恢复序列高信号

2022-09-11 神经科病例撷英拾粹 神经科病例撷英拾粹

74岁男性,表现为右侧分水岭梗死(初始钆注射MRI,图)。肾功能正常。4小时后的MRI可见同侧血管周围间隙(PVS)和蛛网膜下腔液体衰减反转恢复序列(FLAIR)高信号,很可能与卒中相关的延迟钆渗漏有

74岁男性,表现为右侧分水岭梗死(初始钆注射MRI,图)。肾功能正常。4小时后的MRI可见同侧血管周围间隙(PVS)和蛛网膜下腔液体衰减反转恢复序列(FLAIR)高信号,很可能与卒中相关的延迟钆渗漏有关(图)。10天后的MRI可见蛛网膜下腔/血管周围异常完全消退(图)。

FLAIR上卒中相关的蛛网膜下腔和眼部钆渗漏很可能代表血-脑/眼屏障破坏。较早的一则报道描述了卒中后超过1个月的MRI上的PVS钆渗漏。在蛛网膜下腔和PVS中观察到的与卒中相关的血-脑屏障渗漏可能涉及类淋巴系统(在 CSF-间质液交换中发挥作用)。

(图:初始MRI[注射钆用于磁共振血管造影]可见右侧梗死[A:弥散加权成像]和血管周围间隙[PVS][B:T1加权成像;C:液体衰减反转恢复序列(FLAIR)];D-F:4小时后,MRI可见同侧蛛网膜下腔[箭]和深部和皮质下PVS[箭头]钆渗漏,表现为FLAIR高信号;G-I:10天后观察到蛛网膜下腔/血管周围FLAIR异常完全消退)

参考文献

Nistorec L, Renard D, Parvu T. Perivascular and Subarachnoid Fluid-Attenuated Inversion Recovery Hyperintensities Related to Delayed Gadolinium Leakage After Stroke. Neurology. 2021 Nov 23;97(21):1000-1001. 

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    2022-11-02 yinhl1978
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    2022-09-11 1462c028m99(暂无昵称)

    学习了

    0

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    2022-09-11 1462c028m99(暂无昵称)

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Stroke:中国绝经前妇女子宫和卵巢切除术后卒中和心脏病风险

在接受过HA或HBO治疗的女性中患缺血性卒中和IHD的风险更高,在讨论这些干预措施时应该对这些风险进行评估。

Stroke:子宫内膜异位症与卒中发生风险的关系

研究人员观察到子宫内膜异位症女性卒中的风险升高。妇女及其保健提供者应了解子宫内膜异位症的病史,最大限度地提高心血管疾病的初级预防,并讨论心血管疾病的体征和症状。

JAMA:血管内治疗前经静脉使用替罗非班并不显著改善大血管闭塞性卒中患者的临床结局(RESCUE BT研究)

血管内治疗毋庸置疑是急性前循环大血管闭塞的一线治疗手段。然而,不论是采用支架取栓、导管抽吸,亦或是机械碎栓、血管成形等技术,都有可能损害血管内皮,致使血栓形成,甚者发生血管再次闭塞。既往研究报道术后2

Ann Intern Med:非心脏手术后房颤与卒中、心律失常和死亡的关系

与非手术房颤相比,非心脏手术后房颤与血栓栓塞的风险相似。该研究的结果对术后房颤的早期和后续治具有重要的意义。

卒中血栓形成的病理生理学机制

根据作为卒中主要原因的血栓类型,患者的早期进展、对急性期治疗的影响、预后和二级预防各不相同。明确血栓的发生机制、组成成分及重要因素对缺血性脑卒中患者的正确诊断和治疗至关重要。

Eur Heart J:无房颤的射血分数降低心力衰竭患者卒中预测

研究人员有可能在没有房颤的HFrEF患者中识别出与未进行抗凝治疗的房颤患者相同卒中风险的亚组。