Eur Heart J:癌症患者与经皮冠状动脉介入治疗

2018-12-01 xing.T MedSci原创

由此可见,在接受PCI治疗的患者中癌症较为常见,并且癌症的预后影响对于癌症的类型、有无转移以及当前和既往诊断都是特异性的。对癌症患者的治疗应该个性化,并且需要心脏病专家和肿瘤学家之间的密切合作。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,该研究旨在根据癌症类型和有无转移,评估接受经皮冠状动脉介入治疗(PCI)的既往或当前癌症患者的时间趋势和结局。

在2004年至2014年期间全国住院患者样本中接受PCI的个体被纳入该研究。多变量分析用于明确癌症诊断与院内死亡率和并发症之间的关联。

该研究共纳入了6571034例PCI手术患者,当前和既往癌症的比例分别为1.8%和5.8%。两种比率都随着时间的推移而增加,四种最常见的癌症是前列腺癌、乳腺癌结肠癌肺癌。当前肺癌患者的院内死亡率更高(比值比(OR)为2.81,95%置信区间(95%CI)为2.37-3.34)以及任何住院并发症(OR为1.21,95%CI为1.10-1.36)更多,然而,当前结肠癌与任何并发症(OR为2.17,95%CI为1.90-2.48)和出血(OR为3.65,95%CI为3.07-4.35)相关,但与死亡率无关(OR为1.39,95%CI为0.99-1.95)。目前对乳腺癌的诊断与院内死亡率或所研究的任何并发症无显著相关性,前列腺癌仅与出血风险增加有关(OR为1.41,95%CI为1.20-1.65)。既往诊断的肺癌与院内死亡率OR的增加独立相关(OR为1.65,95%CI为1.32-2.05)。

由此可见,在接受PCI治疗的患者中癌症较为常见,并且癌症的预后影响对于癌症的类型、有无转移以及当前和既往诊断都是特异性的。对癌症患者的治疗应该个性化,并且需要心脏病专家和肿瘤学家之间的密切合作。

原始出处:

Jessica E Potts.et al. Percutaneous coronary intervention in cancer patients: a report of the prevalence and outcomes in the United States. Eur Heart J.2018. https://doi.org/10.1093/eurheartj/ehy769

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    2018-12-03 zhaojie88
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    2018-12-03 slcumt
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    2018-12-01 lietome24

    好文,值得点赞,更值得收藏!慢慢领会学习的。给点个赞!

    0

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