Brit J Cancer:高强度间歇训练对睾丸癌幸存者疲劳和生活质量影响研究

2018-05-13 AlexYang MedSci原创

睾丸癌幸存者(TCS)处于癌症相关疲劳、心理障碍和生活质量相关的心理障碍(HRQoL)风险增加的情况中。最近,研究人员调查了高强度的间歇训练(HIIT)在TCS患者中对病人报道的结果(PROs)的影响。之后,研究人员探索了心肺功能作为干预效果的一个调节标记,并挑选了干预效果调节标记的基线特性。研究包括了63名TCS患者,并且随机分配到监督下的HIIT组或者常规护理组中。并在基线点、干预后和跟踪调查

睾丸癌幸存者(TCS)处于癌症相关疲劳、心理障碍和生活质量相关的心理障碍(HRQoL)风险增加的情况中。最近,研究人员调查了高强度的间歇训练(HIIT)在TCS患者中对病人报道的结果(PROs)的影响。之后,研究人员探索了心肺功能作为干预效果的一个调节标记,并挑选了干预效果调节标记的基线特性。

研究包括了63名TCS患者,并且随机分配到监督下的HIIT组或者常规护理组中。并在基线点、干预后和跟踪调查3个月时评估了PROs包括的CRF、抑郁、焦虑、压力、自尊和睡眠情况以及HRQoL。研究发现,TCS(平均诊断后7年)完成了99%的训练环节,并且达到了98%的目标训练强度。ANCOVA阐释了与UC比较,HIIT显著改善了干预后的CRF(p=0.003)、自尊(p=0.029)和多个HRQoL模块(ps≤0.05)。对CRF(p=0.031)和活力(p=0.015)的影响在3个月的跟踪调查中持续存在。心肺功能的变化能够调节CRF和HRQoL,使其得到改善。在基线点,TCS的CRF影响更大,并且伴随缺乏运动的生活方式、更差的健康状态、更高的睾丸素水平和临床疲劳。

最后,研究人员指出,HIIT能够显著的改善TCS的CRF和HRQoL。心肺功能的调节和临床特性的控制表明了目标训练干预能够优化TCS的PROs。

原始出处:

Scott C Adams, Darren S DeLorey, Margie H Davenport et al. Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors. Brit J Cancer. 08 May 2018.

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    2018-05-18 一个字-牛

    学习了谢谢分享

    0

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    2018-05-15 tamgche
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    2018-05-15 zhangph
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    2018-05-15 aids219
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    2018-05-13 329523732

    不错

    0

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