JAHA:环境空气污染对儿童和青少年血压的影响

2021-05-05 MedSci原创 MedSci原创

短期和长期接触某些环境空气污染物可能会升高儿童和青少年的BP。

既往研究已经调查了儿童和青少年环境空气污染与血压(BP)之间的关联,但是,结果并不一致。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员旨在进行系统回顾和荟萃分析,以评估儿童和青少年中短期和长期环境空气污染物暴露与BP值之间的关系。

研究人员在2020年9月6日之前检索了PubMed、Web of Science和Embase数据库。两名作者独立检索和选择了研究,提取了数据并评估了研究质量。根据空气污染物(NO2、直径≤10μm或≤2.5μm的颗粒物(PM))的组成和暴露时间将研究分为几类。研究人员计算了β回归系数(β)及其95%CI,以评估空气污染物每增加10μg/m3时的效应强度。

该荟萃分析纳入了36650篇文献中的14篇文献。荟萃分析显示,直径≤10μm(β=0.267;95%CI为0.033‒0.501)的PM短期暴露与收缩压升高有关。此外,长期暴露于直径≤2.5μm(β=1.809; 95%CI为0.962‒2.655)的PM、直径≤10μm(β=0.526; 95%CI为0.095-0.958)的PM和NO2(β=0.754; 95%CI为0.541-0.968)与收缩压值相关,并且长期暴露于直径≤2.5μm的PM(β=0.931; 95%CI为0.157-1.705)和直径≤10μm的PM(β=0.378; 95%CI为0.022-0.735)与舒张压相关。

由此可见,该研究表明,短期和长期接触某些环境空气污染物可能会升高儿童和青少年的BP。

原始出处:

Miao Huang.et al.Effects of Ambient Air Pollution on Blood Pressure Among Children and Adolescents: A Systematic Review and Meta‐Analysis.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.017734

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    2021-05-07 zhaohui6731
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    2021-05-05 ms7000000221867473

    学习了

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