JAHA:每日平均温度和温度变化与急性主动脉夹层风险的关联

2021-06-26 MedSci原创 MedSci原创

寒冷显著增加了AAD风险,这可能有助于早期预防和及时诊断该疾病。

环境温度与血管疾病之间的关联已被充分证实,但目前缺乏关于急性主动脉夹层 (AAD) 发病风险随时间变化的证据。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员根据来自同济医院(中国武汉)的2120名诊断为AAD的患者数据进行了一项为期8年的时间序列研究。

研究人员测量了研究区的每日气象参数,并应用斯皮尔曼等级相关分析来评估每日气象数据与空气污染指标之间的关联。拟泊松回归后的分布式滞后非线性模型用于描述非线性暴露-反应关系以及日平均温度和温度变化对AAD发生的滞后效应。

温度与AAD风险之间的暴露-反应关系

考虑到25天的滞后效应,相比于25°C的较低或较高温度不会改变AAD的发病风险。日平均气温对AAD发病率的滞后效应在2天内有统计学意义,日平均气温对AAD风险的影响在当天效应最大。日平均温度与滞后0时AAD发病风险之间的暴露-反应曲线显示,极冷温度(第2.5个百分位数,0.5°C)显著增加了总体AAD(相对风险为1.733;95%CI为1.130–2.658)和A型夹层(相对风险为3.951;95%CI为1.657–9.418)风险。1周内的温度变化不影响AAD的总体发病风险。

由此可见,寒冷显著增加了AAD风险,这可能有助于早期预防和及时诊断该疾病。


原始出处:

Xinyu Yu.et al.Association of Daily Mean Temperature and Temperature Variability With Onset Risks of Acute Aortic Dissection.J AM HEART ASSOC.2021.https://www.ahajournals.org/doi/10.1161/JAHA.120.020190

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    2021-06-28 zhaohui6731
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1949259, encodeId=a54019492592c, content=<a href='/topic/show?id=88e0521825b' target=_blank style='color:#2F92EE;'>#急性主动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52182, encryptionId=88e0521825b, topicName=急性主动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=shuangle, createdTime=Sat Apr 16 19:45:50 CST 2022, time=2022-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268565, encodeId=8c9c12685655d, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415758, encodeId=e9031415e5811, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519620, encodeId=32ee15196200d, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977220, encodeId=75779e7220ea, content=<a href='/topic/show?id=a5ae23159d2' target=_blank style='color:#2F92EE;'>#主动脉夹层#</a>这种研究也能发表??真是奇, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23159, encryptionId=a5ae23159d2, topicName=主动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 27 09:19:24 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977215, encodeId=39999e7215e4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/52f05a6c3dc84a21914c8db97f942183/ea6d7fb8aee1422ebdb19e406fd3565e.jpg, createdBy=54462178408, createdName=340133210_47538571, createdTime=Sun Jun 27 09:08:11 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977212, encodeId=8f179e721289, content=老年人还是生活在天气热一点的地方好一些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun Jun 27 09:03:52 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977196, encodeId=54d49e719636, content=环境与人息息相关, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Jun 27 06:43:25 CST 2021, time=2021-06-27, status=1, ipAttribution=)]
    2021-06-27 小小医者

    #主动脉夹层#这种研究也能发表??真是奇

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1949259, encodeId=a54019492592c, content=<a href='/topic/show?id=88e0521825b' target=_blank style='color:#2F92EE;'>#急性主动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52182, encryptionId=88e0521825b, topicName=急性主动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=shuangle, createdTime=Sat Apr 16 19:45:50 CST 2022, time=2022-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268565, encodeId=8c9c12685655d, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1415758, encodeId=e9031415e5811, content=<a href='/topic/show?id=04812314540' target=_blank style='color:#2F92EE;'>#主动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23145, encryptionId=04812314540, topicName=主动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77603112682, createdName=circumcision, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519620, encodeId=32ee15196200d, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Mon Jun 28 14:45:50 CST 2021, time=2021-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977220, encodeId=75779e7220ea, content=<a href='/topic/show?id=a5ae23159d2' target=_blank style='color:#2F92EE;'>#主动脉夹层#</a>这种研究也能发表??真是奇, beContent=null, objectType=article, channel=null, level=null, likeNumber=137, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23159, encryptionId=a5ae23159d2, topicName=主动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sun Jun 27 09:19:24 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977215, encodeId=39999e7215e4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210627/52f05a6c3dc84a21914c8db97f942183/ea6d7fb8aee1422ebdb19e406fd3565e.jpg, createdBy=54462178408, createdName=340133210_47538571, createdTime=Sun Jun 27 09:08:11 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977212, encodeId=8f179e721289, content=老年人还是生活在天气热一点的地方好一些。, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210703/9c448fe1b3b54fd7bc9477662f4861bb/4bdadad22bfd46f2921aabb4c40265d3.jpg, createdBy=a8d81938466, createdName=weigq, createdTime=Sun Jun 27 09:03:52 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977196, encodeId=54d49e719636, content=环境与人息息相关, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b7a31928393, createdName=学医无涯, createdTime=Sun Jun 27 06:43:25 CST 2021, time=2021-06-27, status=1, ipAttribution=)]
    2021-06-27 340133210_47538571

    学习了

    0

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    2021-06-27 weigq

    老年人还是生活在天气热一点的地方好一些。

    0

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    2021-06-27 学医无涯

    环境与人息息相关

    0

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