CSCO 2014:R0切除术在胃癌肝转移患者中的应用和进展

2014-09-19 廖莉莉 中国医学论坛报

        复发转移性胃癌">胃癌综合治疗论坛(2楼3号会议室)时间:9月20日10:30~10:45         报告者:天津医科大学附属肿瘤医院黄鼎智 近期统计数据揭示中国胃癌发病率为第2位(36.21例/10万人

        复发转移性胃癌">胃癌综合治疗论坛(2楼3号会议室)时间:9月20日10:30~10:45

        报告者:天津医科大学附属肿瘤医院黄鼎智

近期统计数据揭示中国胃癌发病率为第2位(36.21例/10万人),死亡率为第3位(25.88例/10万人)。手术是胃癌唯一的根治性手段,不同期别的胃癌术后生存差异明显,IA期、IB期、II期、IIIA期、IIIB期、IV期胃癌患者的5年生存率分别是78%、58%、34%、20%、8%和7%。对于转移性胃癌患者,化疗是最主要治疗,遗憾的是传统化疗药物姑息治疗效果极为有限,客观缓解率约30%~40%,中位生存期仅为9~13个月。其中仅有肝转移的胃癌患者,姑息化疗5年生存率不足2%。传统化疗疗效已接近瓶颈,即使联合靶向药物疗效提高仍然十分有限。

随着对实体瘤生物学行为特征认识的提高和治疗的发展,部分转移性实体瘤的治疗取得巨大进步。可R0切除的结直肠癌肝转移患者的中位生存期达到35个月,5年生存率可达30%~50%。近年来一些研究探索了外科根治性切除在胃癌肝转移患者中的应用,本文拟就外科手术在可R0切除胃癌肝转移患者中的研究作一回顾,探讨根治术在肝转移患者中的价值和意义。

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=209558, encodeId=b719209558c2, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sun Jun 11 23:42:29 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066116, encodeId=810d2066116dd, content=<a href='/topic/show?id=e1178324438' target=_blank style='color:#2F92EE;'>#胃癌肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83244, encryptionId=e1178324438, topicName=胃癌肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=951d2500061, createdName=12498717m66(暂无昵称), createdTime=Mon May 04 21:06:00 CST 2015, time=2015-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876685, encodeId=7cc918e668550, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Sep 01 22:06:00 CST 2015, time=2015-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443790, encodeId=c1c01443e905b, content=<a href='/topic/show?id=6b058150307' target=_blank style='color:#2F92EE;'>#肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81503, encryptionId=6b058150307, topicName=肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea155117075, createdName=ms6747015003810650, createdTime=Sun Sep 21 00:06:00 CST 2014, time=2014-09-21, status=1, ipAttribution=)]
    2017-06-11 luominglian113

    学习了,谢谢分享

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=209558, encodeId=b719209558c2, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sun Jun 11 23:42:29 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066116, encodeId=810d2066116dd, content=<a href='/topic/show?id=e1178324438' target=_blank style='color:#2F92EE;'>#胃癌肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83244, encryptionId=e1178324438, topicName=胃癌肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=951d2500061, createdName=12498717m66(暂无昵称), createdTime=Mon May 04 21:06:00 CST 2015, time=2015-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876685, encodeId=7cc918e668550, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Sep 01 22:06:00 CST 2015, time=2015-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443790, encodeId=c1c01443e905b, content=<a href='/topic/show?id=6b058150307' target=_blank style='color:#2F92EE;'>#肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81503, encryptionId=6b058150307, topicName=肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea155117075, createdName=ms6747015003810650, createdTime=Sun Sep 21 00:06:00 CST 2014, time=2014-09-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=209558, encodeId=b719209558c2, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sun Jun 11 23:42:29 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066116, encodeId=810d2066116dd, content=<a href='/topic/show?id=e1178324438' target=_blank style='color:#2F92EE;'>#胃癌肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83244, encryptionId=e1178324438, topicName=胃癌肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=951d2500061, createdName=12498717m66(暂无昵称), createdTime=Mon May 04 21:06:00 CST 2015, time=2015-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876685, encodeId=7cc918e668550, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Sep 01 22:06:00 CST 2015, time=2015-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443790, encodeId=c1c01443e905b, content=<a href='/topic/show?id=6b058150307' target=_blank style='color:#2F92EE;'>#肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81503, encryptionId=6b058150307, topicName=肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea155117075, createdName=ms6747015003810650, createdTime=Sun Sep 21 00:06:00 CST 2014, time=2014-09-21, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=209558, encodeId=b719209558c2, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=550d2008262, createdName=luominglian113, createdTime=Sun Jun 11 23:42:29 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066116, encodeId=810d2066116dd, content=<a href='/topic/show?id=e1178324438' target=_blank style='color:#2F92EE;'>#胃癌肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83244, encryptionId=e1178324438, topicName=胃癌肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=951d2500061, createdName=12498717m66(暂无昵称), createdTime=Mon May 04 21:06:00 CST 2015, time=2015-05-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1876685, encodeId=7cc918e668550, content=<a href='/topic/show?id=67c5319121e' target=_blank style='color:#2F92EE;'>#切除术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31912, encryptionId=67c5319121e, topicName=切除术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Tue Sep 01 22:06:00 CST 2015, time=2015-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1443790, encodeId=c1c01443e905b, content=<a href='/topic/show?id=6b058150307' target=_blank style='color:#2F92EE;'>#肝转移#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81503, encryptionId=6b058150307, topicName=肝转移)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ea155117075, createdName=ms6747015003810650, createdTime=Sun Sep 21 00:06:00 CST 2014, time=2014-09-21, status=1, ipAttribution=)]

相关威廉亚洲官网

CSCO 2014:肺癌个体化治疗时代的检测变革

非小细胞肺癌论坛(1楼1E会议室)时间:9月19日10:55~11:15 报告者:北京大学肿瘤医院  王洁 对肺癌驱动基因的深入研究导致了基因检测的巨大变革,肺癌驱动基因的检测正在经历从单基因到多基因、从静态到动态、从定性到定量、从组织水平到单细胞水平的变革。随着组织病理学到分子病理学的发展,NSCLC不再被认为是一个疾病而是由不同驱动基因作用的一组疾病。检测技术的变革已经并将继

CSCO 2014:局部进展期胃癌放化疗的是与非

复发转移性胃癌">胃癌综合治疗论坛(2楼3号会议室)时间:9月20日11:30~11:45 报告者:中山大学附属第一医院彭建军 我国是胃癌大国,每年大约有40万新发病例及30万死亡病例。在接受手术的患者中,约91%胃癌患者死于术后复发。胃癌复发有多种方式,分为局部复发、肝转移复发、肝转移以外的血行转移性复发、腹膜播种、淋巴结转移复发、其他等6种,其局部(手术野)复发和残胃复发合称为局部复

CSCO 2014:青年医师论坛乳腺癌专场:多学科团队,全方位交流

两大特色,三种希望 青年医师论坛——乳腺癌">乳腺癌专场策划负责人、江苏省人民医院殷咏梅 一场论坛,两大特色 今年CSCO青年医师论坛的乳腺癌专场将会具有两大特色。首先是乳腺癌全程管理的理念,内容安排从术前新辅助治疗到乳腺癌前哨淋巴结相关问题,从辅助治疗到晚期解救治疗,均体现出了乳腺癌全程管理的理念。 各位讲者将分别就新辅助治疗策略和进展、辅助化疗和内分泌治疗进展、转移性乳腺癌化

CSCO 2014:中国学者须重视临床研究数据标准

        临床研究中的数据标准及监管要求论坛策划负责人、北京大学肿瘤医院 朱军 双管齐下,促进临床研究标准化 此次“临床研究中的数据标准及监管要求”论坛主要有两个目的:一是使临床医生对临床药监部门在监管方面有何法规或政策性的特殊要求有所掌握和理解;二是对临床研究工作者进行临床数据标准的继续培训。 在实际

CSCO 2014:《共识》发布,播撒规范化诊疗的“火种”

        胰腺癌">胰腺癌论坛策划负责人、上海交通大学附属第一人民医院王理伟 胰腺癌是高度恶性的肿瘤之一,目前全球范围内的发病率正处于快速上升期。据《2012中国肿瘤登记年报》统计,2009年胰腺癌占我国恶性肿瘤发病率和死亡率的第7位和第6位,预计2030年胰腺癌将成为第2位恶性肿瘤死因。 中国胰腺

CSCO 2014:EGFR基因突变状态未知NSCLC治疗——TKIor化疗?

非小细胞肺癌论坛(1楼1E会议室)时间:9月19日11:45~12:00 报告者:南军事医学科学院附属医院  刘晓晴 目前非小细胞肺癌依据驱动基因EGFR突变状态分为EGFR突变型、EGFR野生型和EGFR状态未知型,在个体化治疗理念主导的当今,临床实践必须依据其EGFR基因状态选择治疗。  在分子生物学指标指导下的个体化治疗时代,williamhill asia 依然不能抛开患者的临床病理特点而