Eur Radiol:诊断胰腺癌就单单开个磁共振检查单?磁共振弹性成像在诊断胰腺癌中价值!

2017-10-31 shaosai MedSci原创

胰腺导管腺癌是常见的一种胰腺癌的类型,它可以分为4期。一期无残留的肿瘤切除生存时间要大大长于其他时期的导管腺癌,因此做好尽早的发现导管腺癌,对患者有着重要的意义。另外人们又常常不能够尽早的发现导管腺癌,能施行一期无肿瘤残存的手术人数只有5%。所以提高导管腺癌的诊断机制对导管腺癌的治愈有着重要的意义。本研究旨在验证MR弹性成像(MRE)并将其与血清CA19-9在鉴别良恶性胰腺肿块的诊断价值,尤其是胰

胰腺导管腺癌是常见的一种胰腺癌的类型,它可以分为4期。一期无残留的肿瘤切除生存时间要大大长于其他时期的导管腺癌,因此做好尽早的发现导管腺癌,对患者有着重要的意义。另外人们又常常不能够尽早的发现导管腺癌,能施行一期无肿瘤残存的手术人数只有5%。所以提高导管腺癌的诊断机制对导管腺癌的治愈有着重要的意义。本研究旨在验证MR弹性成像(MRE)并将其与血清CA19-9在鉴别良恶性胰腺肿块的诊断价值,尤其是胰腺导管内腺癌(PDAC)和肿块型胰腺炎(MFP),并将结果发表在Eur Radiol上。

本研究共纳入了85例经组织病理学检查证实的实性胰腺肿块的患者。评价肿块硬度计硬度比(以肿块硬度/胰腺硬度计算所得)。利用ROC曲线下面积(AUROC)分析诊断准确度。

最终诊断包括54例恶性肿瘤(43例PDAC患者)和31例良性肿块(24例MFP患者)。在鉴别良恶性胰腺肿瘤时,肿块硬度比的诊断价值要高于肿块硬度和血浆CA19-9(AUC: 0.912 vs. 0.845 vs. 0.702; P = 0.026, P < 0.001),尤其是在PDAC和MFP中(AUC: 0.955 vs. 0.882 vs. 0.745; P = 0.026, P = 0.003)。肿块硬度比鉴别PDAC和MFP的敏感性、特异性和准确性均高于0.9。

本研究表明,基于PDAC和MFP各自的机制特征,MRE在鉴别两种病变中具有高效并能够定量分析的价值。

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    2017-11-03 zb1235672

    好知识.值得学习!

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=2045448, encodeId=2bd82045448c5, content=<a href='/topic/show?id=7a32e37586f' target=_blank style='color:#2F92EE;'>#磁共振弹性成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73758, encryptionId=7a32e37586f, topicName=磁共振弹性成像)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc0372, createdName=bnurmamat, createdTime=Tue Mar 06 11:56:00 CST 2018, time=2018-03-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1645959, encodeId=6ec1164595974, content=<a href='/topic/show?id=663550088ef' target=_blank style='color:#2F92EE;'>#弹性成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50088, encryptionId=663550088ef, topicName=弹性成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0eb23278887, createdName=tamgche, createdTime=Mon Dec 18 01:56:00 CST 2017, time=2017-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=258299, encodeId=38f025829928, content=好知识.值得学习!, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59321624668, createdName=zb1235672, createdTime=Fri Nov 03 08:46:39 CST 2017, time=2017-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341587, encodeId=0292134158e10, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Thu Nov 02 12:56:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1486093, encodeId=d6cf14860930e, content=<a href='/topic/show?id=e633e37655a' target=_blank style='color:#2F92EE;'>#磁共振检查#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73765, encryptionId=e633e37655a, topicName=磁共振检查)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Thu Nov 02 12:56:00 CST 2017, time=2017-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257612, encodeId=83f425e61242, content=不错的文章值得一读, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Tue Oct 31 22:48:51 CST 2017, time=2017-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=257604, encodeId=798025e6044e, content=谢谢分享知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuF63NQckT5BOaic1el7cRelbpr859YXtZQHQSaWnqZCRPOZzDBcjsBNx7AFefLHh1UvMPS4kPP0BG/0, createdBy=47831990981, createdName=1e1a50a1m36(暂无匿称), createdTime=Tue Oct 31 22:12:38 CST 2017, time=2017-10-31, status=1, ipAttribution=)]
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    2017-10-31 1e1b8538m79(暂无匿称)

    不错的文章值得一读

    0

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    2017-10-31 1e1a50a1m36(暂无匿称)

    谢谢分享知识

    0

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