JACC:左室舒张功能不全可预测系统性硬化症患者的死亡风险

2018-10-09 MedSci MedSci原创

原发性心脏疾病在系统性硬化症(SSc)中很常见,同时也是导致死亡的主要原因。本研究的目的旨在评估SSc患者的心脏舒张功能及其对死亡率的影响。本研究纳入了奥斯陆大学附属医院2003年至2016年的SSc患者,并对其心脏功能进行随访评估,最终,共对275名SSc患者的基础心脏舒张功能进行了评估,对186名SSc患者进行了随访评估。分析结果显示,研究初始共有46名(17%)患者存在心脏舒张功能不全(DD

原发性心脏疾病在系统性硬化症(SSc)中很常见,同时也是导致死亡的主要原因。本研究的目的旨在评估SSc患者的心脏舒张功能及其对死亡率的影响。

本研究纳入了奥斯陆大学附属医院2003年至2016年的SSc患者,并对其心脏功能进行随访评估,最终,共对275名SSc患者的基础心脏舒张功能进行了评估,对186名SSc患者进行了随访评估。分析结果显示,研究初始共有46名(17%)患者存在心脏舒张功能不全(DD),195名(71%)患者的舒张功能正常。经过平均3.4年时间的随访,DD的比例从17%增至29%。随访期间,有57%的初始有DD的患者死亡,而心脏舒张功能正常的患者有13%出现死亡。经多元回归分析发现,DD是SSc死亡的强预测因子。

研究结果显示,心脏舒张功能不全在系统性硬化症患者中很常见,并与死亡率的增高相关。

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    2019-08-29 hbwxf
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    2019-04-22 yahu
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