BMC Nephrol:白细胞计数可预测肾脏病

2017-06-13 许菁 中国循环杂志

北京大学第一医院学者研究发现,白细胞计数与中国社区人群肾功能急剧下降有关。研究者指出,早期监测高白细胞计数可能对CKD风险评估和预防有价值。本研究的3768名受试者中,48.6%有高血压,17.4%有糖尿病。基线白细胞计数为(6.1 ± 1.5) × 109/L。随访2.3年,肾功能降低、eGFR迅速下降、CKD发生率分别为7.7%、20.9%和0.8%,白细胞计数与之有关。进一步分析显示,受试者

北京大学第一医院学者研究发现,白细胞计数与中国社区人群肾功能急剧下降有关。

研究者指出,早期监测高白细胞计数可能对CKD风险评估和预防有价值。

本研究的3768名受试者中,48.6%有高血压,17.4%有糖尿病。基线白细胞

计数为(6.1 ± 1.5) × 109/L。

随访2.3年,肾功能降低、eGFR迅速下降、CKD发生率分别为7.7%、20.9%和0.8%,白细胞计数与之有关。

进一步分析显示,受试者白细胞计数为最高四分位时的eGFR迅速下降(每年

降低>3ml/min·1.73m2)风险增加49%,肾功能降低(eGFR降低50%

或>5ml/min·1.73m2)风险增加1倍,新发CKD增加近4倍。

白细胞计数每增加1× 109/L,则肾功能降低、eGFR迅速下降、CKD发生风险分别增加14%、11%和36%。

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    2017-06-13 sillywu

    这篇文章很有参考意义啊。值得借鉴

    0

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    2017-06-13 llaq

    学习了

    0

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    2017-06-13 1e1a50a1m36(暂无匿称)

    白细胞计数与中国社区人群肾功能急剧下降有关。

    0