Behavioural Brain Research:7周的集中注意力冥想训练引起初学者大脑皮质重组

2020-08-08 MedSci原创 MedSci原创

冥想可能会增加幸福感减轻压力

基于冥想的技术已越来越多地应用于心理治疗计划中。但是,不同的冥想风格和导致了各种各样的形态计量学发现。作者旨在阐明由短期冥想训练引起的皮质重组过程和轴突完整性改变,并且受益于集中注意力冥想(FAM)。冥想者和非冥想者之间的形态学差异与冥想练习的数量和持续时间有关。变化最稳定的大脑区域包括额叶,前额内侧皮层(mPFC)和海马皮层,这些区域与自我意识,自我调节和情节性记忆有关。与冥想有关的大脑改变包括GM量,皮质厚度和回旋,以及WM完整性。弥散加权成像(DWI)是一种非侵入性MRI技术,用于通过量化称为分数各向异性(FA)的轴突水分子的限制来评估微结构的连通性。

方法:对27位健康,未曾参加过冥想的健康参与者(年龄:43±12.4岁),参加FAM冥想训练之前和之后,进行了3次T MRI检查,包括T1-MPRAGE和扩散加权序列。所有参与者完成了14场指导性冥想课程,共进行了10.5小时。 参与者报告了在家庭练习中以与正式会议相同的冥想方式进行的其他冥想,平均每天持续24分钟。持续时间:7.3±0.4周。基于体素的形态计量学被用于评估大脑中灰白色物质的变化。个人在两个时间点都填写了问卷,以评估生活质量和自我意识缺陷。研究参与者在第1至第4周进行每天15分钟的日常家庭练习,在第5-8周进行20分钟的日常练习,从第9周到第二次MRI预约,进行FAM进行30分钟。

结果:(i)尾状核和额叶皮质灰质增加(ii)额颞颞区,右前额叶前额皮层和海马旁回的减少。回归分析显示特定改变与状态焦虑水平降低相关。丘脑和邻近结构的FA升高可能是改善了单连接,导致了更高的信息流能力,因为丘脑被认为在将感觉信息传递到大脑皮层中发挥了作用,并参与了情绪加工 。本研究新颖的发现是GM升高相对伴随显着降低的相对模式。冥想队列显示出一些区域的GM密度降低,包括右侧mPFC,顶叶和颞皮层以及右侧海马旁回。最近的功能磁共振成像研究表明,与主动任务相比,在冥想期间,包括前扣带回皮层,梭状回,中颞回和前突在内的DMN大脑区域的活动持续下降活动减少可能会促进依赖于使用的突触的选择性消除,导致GM降低mPFC。

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    2020-08-10 qjddjq
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    2020-08-10 yangshch
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    2020-08-10 lyly0000001

    有意思

    0

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    2020-08-09 长毛小米

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