NEJM:过度诊断减半,能有效筛检前列腺癌!

2021-07-25 MedSci原创 MedSci原创

每年大约有140万男性被诊断为前列腺癌,约37.5万男性死于该病。研究表明,及时筛查可以更早的发现疾病,从而降低前列腺癌死亡的风险。但是目前,使用前列腺特异性抗原(PSA)检测结合传统活检筛查,可能会

每年大约有140万男性被诊断为前列腺癌,约37.5万男性死于该病。研究表明,及时筛查可以更早的发现疾病,从而降低前列腺癌死亡的风险。但是目前,使用前列腺特异性抗原(PSA)检测结合传统活检筛查,可能会导致过度诊断,从而增加了不必要的活检。 过度诊断率高是有组织的前列腺癌筛查的一个关键障碍。带有靶向活检的磁共振成像 (MRI) 已显示出解决这一挑战的潜力,但其在有组织的前列腺癌筛查中的使用意义尚不清楚。 近期,来自瑞典卡罗林斯卡学院(Karolinska Institutet)的研究人员在《新英格兰医学杂志》发表了一项研究。研究表明,磁共振成像(MRI)和靶向活检筛查可能将前列腺癌过度诊断减少一半。该结果也在欧洲泌尿外科协会(the European Association of Urology Congress)大会上公布。 截图来源:The New England Journal of Medicine williamhill asia 进行了一项基于人群的前列腺癌筛查非劣效性试验,其中通过邮件邀请 50 至 74 岁的男性参与;研究者在2018年至2021年间共纳入了12750名年龄在50-74岁的男性,受试者

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    2021-07-25 旺医

    顶刊就是顶刊,谢谢williamhill asia 带来这么高水平的研究报道,williamhill asia 科里同事经常看williamhill asia ,分享williamhill asia 上的信息

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    2021-07-25 misszhang

    前列腺癌相关研究,学习了,谢谢williamhill asia

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1035709, encodeId=344a1035e099d, content=顶刊就是顶刊,谢谢williamhill asia 带来这么高水平的研究报道,williamhill asia 科里同事经常看williamhill asia ,分享williamhill asia 上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Sun Jul 25 23:42:21 CST 2021, time=2021-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1041051, encodeId=416410410510f, content=前列腺癌相关研究,学习了,谢谢williamhill asia , beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sun Jul 25 23:42:21 CST 2021, time=2021-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002597, encodeId=0a69100259e7a, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=441e5542088, createdName=小小毛虫, createdTime=Sun Jul 25 22:15:32 CST 2021, time=2021-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1002582, encodeId=a86a1002582f2, content=认真学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6EF3hKja8nER8RMzxQdria9eCYFhgLTLsDOeqnvIYdeLDz5eP6EnicLuE5gibiawgno4zUA0jAR7Nbtp2llQ9fs3Mk/0, createdBy=278f1986883, createdName=医鸣惊人, createdTime=Sun Jul 25 21:22:54 CST 2021, time=2021-07-25, status=1, ipAttribution=)]
    2021-07-25 小小毛虫

    学习

    0

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    2021-07-25 医鸣惊人

    认真学习了

    0

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盘点:近期前列腺癌与治疗进展(九)

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Radiology:MR弹性成像在前列腺癌中的应用

自2007年以来,全世界前列腺癌(PCa)的发病率增加了42%。早期和准确的诊断对于预后和治疗方案的制定非常重要。

Prostate:半自动组织芯片对患有糖尿病前列腺癌患者进行SRSF-1和微血管密度免疫组化分析

前列腺癌(PC)仍然是2020年男性人群中诊断的第一大癌症。多年来,已经确定了许多风险因素,包括高血压、代谢综合征、肥胖。另外,糖尿病认为是能够决定肿瘤细胞结构一致变化的风险因素。

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在进行机器人辅助前列腺根治术(RARP)时,使用手术夹对侧前列腺蒂进行无热解剖,并在盆腔淋巴结清扫术(PLND)期间进行结扎已成为手术过程的金标准。夹子的使用是为了防止无髓神经纤维和淋巴结的热损伤。

Prostate Cancer P D:通过机器学习技术改善前列腺癌的诊断

使用血液检测前列腺特异性抗原(PSA)来早期检测前列腺癌,可以诊断较早期和器官限制阶段的前列腺癌。然而,使用PSA作为前列腺活检决定的唯一工具,也导致了很多不必要的活检和对无痛性前列腺癌的过度诊断。最