AGS 2016:一线降压药不会增加老年人跌倒损伤风险,但是二线降压药会

2016-07-06 Seven L 译 MedSci原创

根据美国老年学会会议上提出的研究,对于老年人跌倒受伤,一线抗高血压药物可能是安全的。俄勒冈州立大学的David S. Lee博士和他的同事们发现,二线高血压会增加各年龄组严重跌倒损伤的风险。他们对26408名年龄在50至85岁的参与者进行了研究,评估一线和二线降压药、他汀类药物和镇静剂对人群跌倒损伤风险的影响。结果表明,他汀类药物与一线抗高血压药不会增加所有参与者的严重跌倒受伤风险。数据显示,50

根据美国老年学会会议上提出的研究,对于老年人跌倒受伤,一线抗高血压药物可能是安全的。

俄勒冈州立大学的David S. Lee博士和他的同事们发现,二线高血压会增加各年龄组严重跌倒损伤的风险。

他们对26408名年龄在50至85岁的参与者进行了研究,评估一线和二线降压药、他汀类药物和镇静剂对人群跌倒损伤风险的影响。

结果表明,他汀类药物与一线抗高血压药不会增加所有参与者的严重跌倒受伤风险。

数据显示,50岁未使用药物的人群摔倒受伤风险为1.7% (95% CI, 1.4-2);85岁人群的风险为5.2% (95% CI, 4.3-6.1);而使用二线降压药分别会使风险增加1.5% (95% CI, 0.24-2.7)和2.5% (95% CI, 0.44-4.6)。

此外,镇静剂也会增加50-79岁人群的跌倒受伤风险,但是对于≥80岁人群,没有发现两者间联系。

研究结果表明,在跌倒损伤方面,一线降压药是安全的;但是二线降压药会增加所有年龄组的严重摔伤的绝对风险。

原始出处:


First-line antihypertensives, statins not associated with increased fall risk in older adults.Healio.July 5, 2016

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    2016-10-12 1e0ece0dm09(暂无匿称)

    谢谢分享学习

    0

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    2016-09-16 ylzr123

    文章有深度,赞一个。深入学习探讨。

    0

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    2016-09-09 1e10c84am36(暂无匿称)

    赞!好文章,拜读,深入学习。

    0

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    2016-07-10 黑心天使

    机理是什么呢?各降压药都有低血压的风险呀,体位性低血压的缘故?

    0

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