ACG 2015:慢性便秘是一种胃肠道疾病的预警信号

2015-10-27 zhaoshuang 译 MedSci原创

美国胃肠病学会2015年会上提出的一项新研究提示,成人慢性便秘可能预示着包括缺血性结肠炎、结肠直肠癌、胃癌、肠窒室等一些严重中的胃肠道疾病。Lauren Gerson博士提出,有慢性便秘时,不论年纪大小,有无胃肠道出血、贫血、体重减轻等胃肠道疾病危险信号时,都需要去检查。一些器质性的胃肠道疾病,比如结肠直肠癌,会出现慢性便秘症状,但是慢性便秘却不是发展成为结直肠癌以及其他一些严重的器质性胃肠道疾病

美国胃肠病学会2015年会上提出的一项新研究提示,成人慢性便秘可能预示着包括缺血性结肠炎、结肠直肠癌、胃癌、肠窒室等一些严重中的胃肠道疾病。

Lauren Gerson博士提出,有慢性便秘时,不论年纪大小,有无胃肠道出血、贫血、体重减轻等胃肠道疾病危险信号时,都需要去检查。一些器质性的胃肠道疾病,比如结肠直肠癌,会出现慢性便秘症状,但是慢性便秘却不是发展成为结直肠癌以及其他一些严重的器质性胃肠道疾病的风险因素。在美国,大约有15%的人有慢性便秘表现。

她的研究小组从从Humedica电子医疗记录SmartFile数据库对12838名18-50岁,从2008年到2013年至少维持了24个月慢性便秘随访治疗的成年患者进行了研究。

研究发现在5/6的疾病类别中,慢性便秘患者胃肠道疾病的风险明显高于没有慢性便秘的患者。虽然炎性肠道疾病引起严重胃肠道疾病的风险更高,但差异不显著(风险比 1.59)

慢性便秘患者的胃肠道疾病风险表

胃肠道疾病            风险比
缺血性结肠炎         7.68
结肠直肠癌           6.26
胃癌                 5.04
肠憩室炎             5.06
复合型胃肠道疾病     3.28

这些关系之前已经有实验证实过,但是没有详细探讨慢性便秘与这些疾病之间的风险比。

Lauren Gerson提出,肠窒室的窒息炎与慢性便秘之间有联系并不让人觉得诧异,因为这类病人往往会逐渐变胖并且活动力下降。但是慢性便秘与胃肠道癌症以及缺血性结肠炎之间的关系如此密切,确实令人惊讶。她们还将继续提取更多的信息观察便秘的持续时间与特定的胃肠道疾病之间的关系,这也是她们研究的最终目标。

原始出处:

Neil Osterweil.Chronic Constipation a Warning Sign for GI Disorders.Medscape Medical News.October 26, 2015

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    2015-12-30 xyfg98

    0

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    2015-11-05 maivera

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-04 Wei Junhui

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-04 Wei Junhui

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-04 Wei Junhui

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-04 Wei Junhui

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-04 Wei Junhui

    0

  10. [GetPortalCommentsPageByObjectIdResponse(id=1666225, encodeId=f737166622513, content=<a href='/topic/show?id=9a42833423a' target=_blank style='color:#2F92EE;'>#胃肠道疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=80, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83342, encryptionId=9a42833423a, topicName=胃肠道疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Sun Mar 20 22:48:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1685516, encodeId=100f168551613, content=<a href='/topic/show?id=33ec184597' target=_blank style='color:#2F92EE;'>#ACG#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1845, encryptionId=33ec184597, topicName=ACG)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a63228213450, createdName=1249842em18(暂无昵称), createdTime=Sat Sep 03 02:48:00 CST 2016, time=2016-09-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50398, encodeId=c41950398dd, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fe261399236, createdName=xyfg98, createdTime=Wed Dec 30 12:46:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42568, encodeId=87b842568dc, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=144, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160713/IMG578519F1E84C63307.jpg, createdBy=331b1635963, createdName=maivera, createdTime=Thu Nov 05 00:11:00 CST 2015, time=2015-11-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42554, encodeId=cd27425546b, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42555, encodeId=34514255504, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42556, encodeId=a8754255624, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=135, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42557, encodeId=19054255e44, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42558, encodeId=3ce442558be, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=160, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151016/IMG56205A89715F55916.jpg, createdBy=23dd1656569, createdName=Wei Junhui, createdTime=Wed Nov 04 21:48:00 CST 2015, time=2015-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=42213, encodeId=3a8a422136b, content=我也会出现, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ded71629504, createdName=nizongzan, createdTime=Mon Nov 02 12:44:00 CST 2015, time=2015-11-02, status=1, ipAttribution=)]
    2015-11-02 nizongzan

    我也会出现

    0

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