Stroke:工作压力较大者脑梗死风险增加24%

2015-02-17 MedSci 中国循环杂志

近期有多名医生因工作紧张发生脑出血。而一项纳入近20万人的荟萃分析显示,相对比工作轻松的人而言,工作压力较大的人发生脑梗死的风险要高24%[1]。其实,关于工作压力对心脑血管以及代谢性疾病的报道并不少见。之前有研究表明,工作压力大可增加心脏病发作风险。 去年一项德国学者在5000余人中进行的研究则表明,工作压力大的人比压力小的人发生2型糖尿病的风险要高出45%[2]。研究人员认为,长期负担较大工作

近期有多名医生因工作紧张发生脑出血。而一项纳入近20万人的荟萃分析显示,相对比工作轻松的人而言,工作压力较大的人发生脑梗死的风险要高24%[1]。

其实,关于工作压力对心脑血管以及代谢性疾病的报道并不少见。之前有研究表明,工作压力大可增加心脏病发作风险。

去年一项德国学者在5000余人中进行的研究则表明,工作压力大的人比压力小的人发生2型糖尿病的风险要高出45%[2]。

研究人员认为,长期负担较大工作压力,会影响神经内分泌系统,从而使下丘脑-垂体-肾上腺轴(HPA轴)失调,进而影响到心血管系统,引发代谢紊乱。此外,缺乏运动,饮食不合理等,都可进一步使健康状况雪上加霜。

不过,该项研究并未发现工作压力对脑出血的显著影响,也没有讨论卒中的具体类型。

这项荟萃分析是瑞典学者对1985~2008年间发表的14项研究196,380人进行的研究,平均随访9.2年。

原始出处:


[1] Fransson EI, Nyberg ST, Heikkilä K, et al. Job strain and the risk of stroke: an individual-participant data meta-analysis. Stroke. 2015 Feb;46(2):557-9.

[2] Huth C, Thorand B, Baumert J, et al. Job strain as a risk factor for the onset of tyep 2 diabetes mellitus: findings from the MONICA/KORA Augsburg cohort study. Psychosom Med, 2014, 76:562-8.

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    2015-02-27 xiaoai5777

    好文章,超赞

    0

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    2015-02-19 karmond
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    2015-02-18 午夜星河

    医生压力挺大的

    0

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    2015-02-17 medcardio

    压力会不会导致神经内分泌紊乱?

    0

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    2015-02-17 49.4.167.**

    工作压力危害大

    0

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来自德克萨斯大学健康科学中心、杜克大学、哥伦比亚大学等机构的科学家们,在对青少年抑郁症的研究中发现一种基因的细微改变可以预测大脑对压力的反应。压力可引起诸如抑郁症、创伤后应激障碍和肥胖等健康问题。这项研究发表在8月2日的《自然神经科学》(Nature Neuroscience)杂志上。 科学家们一直认为,有罹患压力相关疾病的倾向是一种遗传性状,或是面对创伤性事件的结果。在这篇文