Circ J:女性是房颤相关的心源性卒中的危险因素

2016-01-25 phylis 译 MedSci原创

目的:CHA2DS2-VASc评分的大小不仅与中风的发病率有关而且与长期预后相关。AF-相关心源性卒中患者性别和初始卒中严重程度相关性尚未研究。本研究旨在探讨多中心注册研究中,心源性卒中患者初始卒中严重程度的危险因素。方法和结果  :在2001年1月到2013年7月间,研究者从日本标准脑卒中登记中心选择了12701例房颤相关的心源性卒中患者(年龄77±10岁;女性为5653)。应用多变量线性回归确

目的:CHA2DS2-VASc评分的大小不仅与中风的发病率有关,还与其长期预后相关。房颤相关心源性卒中患者的性别与初始卒中严重程度相关性尚未被研究。本研究旨在探讨多中心注册研究中,心源性卒中患者初始卒中严重程度的危险因素。

方法和结果  :在2001年1月到2013年7月间,研究者从日本标准脑卒中登记中心选择了12701例房颤相关的心源性卒中患者(年龄77±10岁;女性为5653)。应用多变量线性回归确定入院NHISS分数的指标。NHISS分数与CHA2DS2-VASc分数呈正相关(ρ= 0.197)。女性患者比男性患者神经功能障碍更严重(NIHSS评分,中位数[平均间距范围]:14[5-22] vs 8[3-18])。多变量回归分析显示高龄(标准偏回归系数β:0.162)、女性(β:0.120)、糖尿病(β:0.020)、血脂代谢异常(β:-0.076)、充血性心衰(β:0.039)和血管性疾病(β:0.030),先前卒中/TIA(β:0.085)和先前应用口服抗凝药(β:-0.020)与入院NIHSS相关。

结论:女性与房颤相关的心源性脑卒中的初始神经损伤严重程度相关。


原文出处:

Nezu T, Hosomi N, et al. Greater Severity of Neurological Defects in Women Admitted With Atrial Fibrillation-Related Stroke. Circ J. 2015 Dec 25.

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    2016-01-27 mhm295
  3. [GetPortalCommentsPageByObjectIdResponse(id=60434, encodeId=2592604344b, content=我仔细看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=154, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0e471683900, createdName=mingliqinmian, createdTime=Wed Jan 27 09:55:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593418, encodeId=840a15934183e, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Wed Jan 27 02:12:00 CST 2016, time=2016-01-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=60045, encodeId=2ff160045a0, content=关爱女性, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Jan 26 20:54:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59644, encodeId=148b596444a, content=这个值得关注!关爱女性, beContent=null, objectType=article, channel=null, level=null, likeNumber=136, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=59121683644, createdName=doctording1, createdTime=Tue Jan 26 16:33:00 CST 2016, time=2016-01-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59385, encodeId=4f34593850f, content=又是与雌激素有关啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4371683642, createdName=文医生, createdTime=Tue Jan 26 13:47:00 CST 2016, time=2016-01-26, status=1, ipAttribution=)]
    2016-01-26 收获你的美

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    2016-01-26 doctording1

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    2016-01-26 文医生

    又是与雌激素有关啊

    0

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