NEJM:阿米巴肝脓肿-病例报道

2018-12-06 xing.T MedSci原创

溶组织内阿米巴感染是由摄入阿米巴囊肿引起的。受污染的食物或水通常是感染来源。

患者为一名29岁感染人体免疫机能丧失病毒的男子,因发热和右上腹疼痛2天而被送到急诊室就诊。



他最近的CD4细胞计数为520个/uL。实验室结果显示天冬氨酸氨基转移酶水平为208 IU/L(参考范围为10-42),丙氨酸氨基转移酶水平为467 IU/L(参考范围为10-40),总胆红素水平为2.4 mg/dl(参考范围为0.2-1.0)。给予对比剂后进行的腹部计算机断层扫描显示肝脏中的环状增强病变提示脓肿(如图A所示)。经皮吸引脓肿后获得红褐色样本(如图B所示)。显微镜检查显示为有伪足的单细胞生物(如图C所示)。抗锥体抗体的间接血细胞凝集试验阳性,滴度为1:256。粪便的聚合酶链反应证实为溶组织内阿米巴感染

溶组织内阿米巴感染是由摄入阿米巴囊肿引起的。受污染的食物或水通常是感染来源。

该患者给予甲硝唑治疗2周,然后用巴龙霉素治疗10天以消除结肠内囊肿。治疗开始后2天患者发热和腹痛消退,随访腹部超声检查肝脓肿面积减小。在90天的随访中,患者没有出现进一步的症状。

原始出处:

Hsin-Hui Wang, et al.Amebic Liver Abscess.N Engl J Med 2018;https://www.nejm.org/doi/full/10.1056/NEJMicm1800360

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    2018-12-07 hunizi009
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