Radiology:海马钙化和脑子不好使有关系吗?

2018-08-24 shaosai MedSci原创

本研究旨在验证海马钙化的危险性,探究海马钙化与认知功能的相关性,将结果发表在Radiology上。

本研究旨在验证海马钙化的危险性,探究海马钙化与认知功能的相关性,将结果发表在Radiology上。

本研究共纳入了来记忆门诊进行就诊的患者。对患者进行认知功能评价及颅脑CT检查。评价患者血管高危因素:高血压糖尿病、高脂血症和吸烟史。认知筛查包括剑桥认知检查(其中包括细微精神检查)。利用CT检查评价海马钙化程度(无、轻度、中度和重度)。对每位患者进行评价,选择最高程度评分。利用Logistic回归分析识别海马钙化的危险因素,利用线性回归评价海马钙化与认知功能的相关性。

结果为,共纳入了1991例患者,女性患者平均年龄为79岁,男性患者平均年龄为77岁。共有380 (19.1%)出现海马钙化。年龄越大(OR, 1.05; 95%CI: 1.03, 1.06)、糖尿病(OR, 1.50; 95% CI: 1.12, 2.00)、吸烟史(OR, 1.49; 95% CI: 1.05, 2.10)与出现海马钙化具有相关性。在出现海马钙化和钙化程度与认知功能间无显着相关性。

本研究表明,年龄越大、糖尿病和吸烟史与海马钙化的风险具有相关性。海马钙化严重程度与有记忆障碍患者的认知功能太差无显着相关性。

原始出处:

de Brouwer EJM, Kockelkoren R, Claus JJ et al.Hippocampal Calcifications: Risk Factors and Association with Cognitive Function.Radiology.DOI:10.1148/radiol.2018172588

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    2018-08-25 一一一多

    有意思,可以看看更大范围的老年人

    0

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    2018-08-24 sunfeifeiyang

    0

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    2018-08-24 龙胆草

    学习谢谢分享

    0

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    2018-08-24 ylzr123

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

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    2018-08-24 yjs木玉

    学习学习再学习

    0

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    2018-08-24 chinadoctorliu_19344479

    学习了,谢谢

    0

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    2018-08-24 深海的鱼

    学习学习学习

    0

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    2018-08-24 1209e435m98(暂无昵称)

    学习了,谢谢分享

    0

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