CHEST:减肥对OSA的影响

2017-02-15 MedSci MedSci原创

肥胖和阻塞性睡眠呼吸暂停(OSA)之间的相互作用是复杂的。虽然通常认为肥胖是OSA的主要原因,并且治疗OSA可以减轻体重的进一步增加,但是新的证据表明这两者之间的关系可能并不如此。肥胖解释了OSA关于呼吸暂停低通气指数定义的60%的不均一性,主要是<50岁的患者,在老年人中更少。此外,OSA患者使用持续气道正压通气的长期治疗与体重增加有关。这种体重增加效应可能是由于消除与OSA相关的呼吸功增

肥胖和阻塞性睡眠呼吸暂停(OSA)之间的相互作用是复杂的。


虽然通常认为肥胖是OSA的主要原因,并且治疗OSA可以减轻体重的进一步增加,但是新的证据表明这两者之间的关系可能并不如此。

肥胖解释了OSA关于呼吸暂停低通气指数定义的60%的不均一性,主要是<50岁的患者,在老年人中更少。

此外,OSA患者使用持续气道正压通气的长期治疗与体重增加有关。这种体重增加效应可能是由于消除与OSA相关的呼吸功增加而引起。

通过医学或外科技术减轻体重,通常可以治愈2型糖尿病,同样,这种体重减轻对于少数睡眠呼吸暂停的患者也有益。下颌长度较短可以预测更好的结果。

然而,伴随体重减轻的整体呼吸暂停低通气指数的轻微下降可能与非仰卧呼吸暂停低通气指数的较大下降相关,因此将一些患者从非体位性OSA转换为体位性OSA(即仅仰卧)。

重要的是,经历手术减肥的患者需要密切监测以预防并发症。

最后,在患有中度至重度肥胖相关OSA的患者中,CPAP联合减轻体重似乎比单独的任一治疗更有益。

原始出处:
Joosten SA, Hamilton GS, Naughton MT. Impact of Weight Loss Management in OSA. Chest. 2017 Feb 6. pii: S0012-3692(17)30157-5. doi: 10.1016/j.chest.2017.01.027.

本文系williamhill asia 医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1929284, encodeId=2f8d19292841c, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Mon Apr 24 00:53:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050597, encodeId=7f09205059ec2, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 17 14:53:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176758, encodeId=351f1e67581e, content=文章真心不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Feb 18 09:47:33 CST 2017, time=2017-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349752, encodeId=ecb81349e521a, content=<a href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Fri Feb 17 11:53:00 CST 2017, time=2017-02-17, status=1, ipAttribution=)]
    2017-04-24 Smile2680
  2. [GetPortalCommentsPageByObjectIdResponse(id=1929284, encodeId=2f8d19292841c, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Mon Apr 24 00:53:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050597, encodeId=7f09205059ec2, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 17 14:53:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176758, encodeId=351f1e67581e, content=文章真心不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Feb 18 09:47:33 CST 2017, time=2017-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349752, encodeId=ecb81349e521a, content=<a href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Fri Feb 17 11:53:00 CST 2017, time=2017-02-17, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1929284, encodeId=2f8d19292841c, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Mon Apr 24 00:53:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050597, encodeId=7f09205059ec2, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 17 14:53:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176758, encodeId=351f1e67581e, content=文章真心不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Feb 18 09:47:33 CST 2017, time=2017-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349752, encodeId=ecb81349e521a, content=<a href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Fri Feb 17 11:53:00 CST 2017, time=2017-02-17, status=1, ipAttribution=)]
    2017-02-18 1e10c84am36(暂无匿称)

    文章真心不错耶

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1929284, encodeId=2f8d19292841c, content=<a href='/topic/show?id=9e604625ab' target=_blank style='color:#2F92EE;'>#Chest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4625, encryptionId=9e604625ab, topicName=Chest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Mon Apr 24 00:53:00 CST 2017, time=2017-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2050597, encodeId=7f09205059ec2, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Fri Mar 17 14:53:00 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=176758, encodeId=351f1e67581e, content=文章真心不错耶, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sat Feb 18 09:47:33 CST 2017, time=2017-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1349752, encodeId=ecb81349e521a, content=<a href='/topic/show?id=3d0d134904c' target=_blank style='color:#2F92EE;'>#OSA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13490, encryptionId=3d0d134904c, topicName=OSA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=322359, createdName=bioon3, createdTime=Fri Feb 17 11:53:00 CST 2017, time=2017-02-17, status=1, ipAttribution=)]
    2017-02-17 bioon3

相关威廉亚洲官网

减肥 So easy,科学家找到降低食欲的基因!

来自澳大利亚和丹麦的国际科学家团队 2 于 13 日发表在《 PNAS 》上的文章报告,他们在蛔虫中发现了一种能够引起饱足感的基因,人类中也存在这一基因,这或许可以帮助williamhill asia 遏制暴饮暴食的冲动,有效治疗肥胖症。

人体“限食”减肥试验证实:“过午不食”是有道理的!

导语:减肥是复杂的,对于许多人来说,限制饮食和增强运动可能是不够的。那么改变用餐时间可行吗?最新一项研究显示:对于那些渴望减肥的人来说,最好的办法是在2点后停止进食,提前摄入食物可以保持食欲水平。即将晚餐的时间提前3到4个小时可以既满足饥饿感,又有助于燃烧脂肪。众所周知,体重超标的人,大脑萎缩可能更严重;体重超标的人,大脑灰质少,自我控制难;体重超标的人,心智比瘦子低很多……但是,减肥是复杂的,对

血管栓塞减肥将取代传统手术减肥

【血管栓塞减肥效果不亚于普通手术减肥】研究人员指出,减肥治疗和代谢干预可能是血管内药物治疗的“下一次革命”。

JAMA SURGERY:减肥手术后是否需要常规使用IS

肥胖和前肠手术的组合使患者接受减肥手术后存在肺部并发症的高风险。术后诱发性肺量测定法(IS)是一种普遍存在的做法;然而,对其有效性几乎目前尚没有足够的证据。近期一项发表在JAMA SURGERY杂志上的文章研究了术后IS对低氧血症、动脉血氧饱和度(Sao2)水平和减肥手术后的肺部并发症的影响。研究采用随机临床试验纳入2015年5月1日至2016年6月30日接受减肥手术的患者。患者在单中心三级转诊教

关于减肥,这里有7个有趣的研究!

关于饮食与减肥,2016年最有趣的7个研究都在这里了,一起来看看吧!

减肥6大误区,很多人都信了!

春节期间或款待朋友,或拜访亲友,人们难免多吃多喝,积攒一些赘肉,每逢佳节胖三斤?呵呵呵,我看不止吧,三公斤都刹不住车,这往往会形成“节后减肥热”。 但是还是有人在减肥时候,为了追求效果,而进了下面这几个误区。