Int J Cardiol:乙型肝炎病毒与冠心病风险!

2018-04-15 xing.T MedSci原创

由此可见,乙肝病毒感染不会增加患者发生冠心病的风险。这种相关性在队列研究和病例对照研究中也不显著。

几项研究报道乙型肝炎病毒(HBV)感染会影响冠心病的风险。然而,它们之间的相关性是存在争议的。近日,心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章。研究人员进行了一项系统评价和荟萃分析,以便更好地理解它们之间的相关性。

研究人员通过检索PubMed、EMBASE和ISI Web of Science等数据库确定了在2017年10月之前发表的相关研究。研究人员采用相对危险度(RR)和相应的95%可信区间(CIs)评估了HBV与冠心病风险之间的关系。研究人员使用随机效应模型来量化这种相关性。

该荟萃分析包含了九篇文献,其中包括65058名HBV感染者和534998名未受HBV感染的对照者。目前的研究不支持HBV感染与冠心病风险之间存在相关性(RR=0.99,9%CI为 0.76–1.22,I2=68.9%)。敏感性分析和“修剪填充法”得出相似的结果。没有观察到发表偏倚的证据。

由此可见,乙肝病毒感染不会增加患者发生冠心病的风险。这种相关性在队列研究和病例对照研究中也不显著。

原始出处:

Yaqin Wang, et al. Hepatitis B virus and the risk of coronary heart disease: A comprehensive systematic review and meta-analyses of observational studies.International Journal of Cardiology.2018. https://doi.org/10.1016/j.ijcard.2018.04.059

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    2018-04-17 雅文博武

    学习了很多先进的医学知识

    0

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    2018-04-16 changjiu

    学习一下谢谢

    0

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    2018-04-16 121832a9m88暂无昵称

    学习了

    0

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    2018-04-15 1e1b8538m79(暂无匿称)

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