J Periodontol:研究再次证实吸烟可加重牙周疾病

2018-05-18 MedSci MedSci原创

既往研究指出压力与慢性牙周炎(CP)之间存在正相关关系,但关于压力与吸烟对牙周病发展的综合影响的研究十分有限。本研究旨在评估CP吸烟者中应激的作用,唾液和血清中皮质醇和白细胞介素-1β的水平。 将75名参与者分别等分为三组:健康对照者(第I组),吸烟者和伴CP的不吸烟者(第II组和第III组),分别进行临床参数的评估,并使用免疫吸附测定(ELISA)测定唾液和血清中皮质醇和IL-1β的水平。

既往研究指出压力与慢性牙周炎(CP)之间存在正相关关系,但关于压力与吸烟对牙周病发展的综合影响的研究十分有限。本研究旨在评估CP吸烟者中应激的作用,唾液和血清中皮质醇和白细胞介素-1β的水平。

将75名参与者分别等分为三组:健康对照者(第I组),吸烟者和伴CP的不吸烟者(第II组和第III组),分别进行临床参数的评估,并使用免疫吸附测定(ELISA)测定唾液和血清中皮质醇和IL-1β的水平。使用Zung的自评抑郁量表问卷评估患者的压力水平。

结果显示,与非CP的吸烟者相比,伴CP的吸烟者探诊深度、临床附着水平、菌斑指数、探诊出血指数和牙龈指数评分较高。与III组相比,II组患者的血清值和IL-1β的水平相对较高。与III组患者相比,II组患者的抑郁评分更高。抑郁评分与Ⅱ组患者唾液皮质醇呈明显正相关。

综上所述,该研究结果表明,伴CP的吸烟患者血清和唾液皮质醇、IL-1β和应激水平明显更高,因此这类患者的牙周疾病风险较高,程度更重。需要进一步研究以探索牙周炎与压力之间的关系。

原始出处:

Bawankar PV, Kolte AP, Kolte RA. Evaluation of Stress, Serum and Salivary Cortisol and Interleukin-1β Levels in Smokers and Non-Smokers with Chronic Periodontitis. J Periodontol. 2018 May 11. doi: 10.1002/JPER.18-0028.
牙周相关的拓展阅读:

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    2019-02-19 feather89
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    2018-05-18 天地飞扬

    了解一下.谢谢分享!

    0

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    2018-05-18 三生有幸9135

    学习一下谢谢分享

    0

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