Eur J Public Health:根据糖尿病治疗威廉亚洲博彩公司 治疗后的心血管事件风险

2015-09-25 phylis 译 MedSci原创

背景:坚持根据糖尿病治疗的推荐威廉亚洲博彩公司 进行治疗,能显著减少患者因心血管疾病住院和死亡的风险。这篇研究的主要目的是评估是否标准化治疗糖尿病能够预测急性心肌梗死(AMI),缺血性卒中(IS),充血性心衰(CHF),下肢截肢(LEA)或以上重大不良心血管事件(MACE)后患者首次住院或死亡的风险,男女之间是否一致?方法:招募2006年91826名(男性46167/女性45659名)住在托斯卡纳区(意大利)的

背景:坚持根据糖尿病治疗的推荐威廉亚洲博彩公司 进行治疗,能显著减少患者因心血管疾病住院和死亡的风险。这篇研究的主要目的是评估是否标准化治疗糖尿病能够预测急性心肌梗死(AMI)、缺血性卒中(IS)、充血性心衰(CHF)、下肢截肢(LEA)或以上重大不良心血管事件(MACE)后患者首次住院或死亡的风险在男女之间是否一致?

方法:研究人员在2006年招募91826名(男性46167/女性45659名)住在托斯卡纳区(意大利)的糖尿病患者。按照威廉亚洲博彩公司 组成指标(GCI)进行检测:每年评估一次HbA1c,至少两年进行一次眼科检查,评估血脂以及尿中微白蛋白,应用Cox比例风险回归模型,在随访的6年间(2007-12),评估坚持GCI的对男女患者因AMI、IS、CHF、LEA、MACE而住院或死亡的风险的影响。

结果:校正协变量后,坚持CGI能够改善男性患者发生AMI、CHF、LEA的预后;而在女性患者中,坚持GCI能够显著降低CHF的住院风险以及IS后的死亡风险。最后,坚持GCI能使男性和女性患者MACE的住院风险下降,下降率分别为15%,11%。相反,坚持GCI似乎对男女患者因MACE住院的死亡率没有影响。

结论:在这项研究中,随访时间超过6年,发现坚持GCI能降低心血管事件的发生,并有证据显示男女之间存在差异。

原文出处:

Seghieri C, Policardo L, Francesconi P, Seghieri G.  Gender differences in the relationship between diabetes process of care indicators and cardiovascular outcomes. Eur J Public Health. 2015 Sep 5.


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    2015-10-09 shizhenshan
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    2015-09-25 lovetcm

    说服力还是较强

    0

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