Am J Resp Crit Care:睡眠呼吸障碍和失眠与高血压和糖尿病的关联

2020-08-17 MedSci原创 MedSci原创

SDB与高血压和糖尿病有关。失眠与高血压有关。这些结果支持将睡眠障碍作为预防和减少疾病的可改变靶标的重要性。

睡眠障碍与高血压和糖尿病有关,且是血管疾病和死亡的主要危险因素。了解西班牙裔/拉丁美洲人中的这些关联具有重要意义,在这些关联中,心血管死亡是导致死亡的主要原因。近日,呼吸内科以及重症医学领域权威杂志Am J Resp Crit Care上发表了一篇研究文章,该研究通过长达6年的随访,旨在调查美国西班牙裔/拉丁美洲人中睡眠呼吸障碍(SDB)和失眠与高血压和糖尿病发生之间的前瞻性关联,并评估这些关联中潜在的性别差异。

研究人员使用调查logistic回归模型分析了来自西班牙裔社区健康研究/拉丁美洲人研究(随访1:2008-2011;随访2:2014-2017)的11623名西班牙裔/拉丁美洲裔参与者的数据,并校正了潜在的混杂因素。研究人员在基线时测量了受试者的SDB(呼吸暂停-呼吸不足指数≥5)和失眠(妇女卫生倡议失眠等级量表≥9)的情况。根据国家威廉亚洲博彩公司 定义了高血压(≥2期)和糖尿病。

在目标人群中,女性占52.6%,基线平均年龄为41.1±14.9岁。与无SDB相比,SDB与高血压的调整后比值比高出1.54(95%置信区间(CI)[1.18,2.00])相关,与糖尿病发生比值比高出1.37(95%CI [1.07,1.75])相关。失眠与高血压有关(OR=1.37;95%CI为[1.11,1.69]),但与糖尿病无关。男性失眠与高血压之间的关联性强于女性。

由此可见,SDB与高血压和糖尿病有关。失眠与高血压有关。这些结果支持将睡眠障碍作为预防和减少疾病的可改变靶标的重要性。

原始出处:

Xiaoyu Li.et al.Associations of Sleep Disordered Breathing and Insomnia with Incident Hypertension and Diabetes: The Hispanic Community Health Study/Study of Latinos.AM J RESP CRIT CARE.2020.https://www.atsjournals.org/doi/abs/10.1164/rccm.201912-2330OC

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    2020-09-15 咻凡

    可以做个研究, 打呼和糖尿病的关系,或者和心脏病的关系

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1754416, encodeId=6dc41e5441692, content=<a href='/topic/show?id=95ea39e304e' target=_blank style='color:#2F92EE;'>#呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39730, encryptionId=95ea39e304e, topicName=呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=02a536676444, createdName=bbwznl, createdTime=Mon Feb 15 00:04:14 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989159, encodeId=7a07198915982, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 03 12:04:14 CST 2020, time=2020-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885470, encodeId=d9f88854e0f5, content=可以做个研究, 打呼和糖尿病的关系,或者和心脏病的关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:15:08 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811062, encodeId=f182811062d4, content=👍🏻, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 16:25:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810860, encodeId=ef318108607c, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:59 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810859, encodeId=279681085948, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810858, encodeId=d776810858c2, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:55 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345578, encodeId=55bb13455e863, content=<a href='/topic/show?id=41b2e2996be' target=_blank style='color:#2F92EE;'>#睡眠呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72996, encryptionId=41b2e2996be, topicName=睡眠呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQBvJI9WesEs5nl29JIJ7mAquShibzBHQmTeHHwZMDlIzc5qoQUhTJOpOwiaxYa9UcibrZviaM7dL7aQ/132, createdBy=35cb2500499, createdName=ms1343860338762272, createdTime=Wed Aug 19 07:04:14 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810007, encodeId=d02a81000ec9, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=dfe85411515, createdName=ms8000001618437429, createdTime=Tue Aug 18 10:16:41 CST 2020, time=2020-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043290, encodeId=764a10432905a, content=谢谢MedSci提供最新的威廉亚洲官网 , beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 17 19:04:14 CST 2020, time=2020-08-17, status=1, ipAttribution=)]
    2020-08-19 ms5000000741733160

    👍🏻

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1754416, encodeId=6dc41e5441692, content=<a href='/topic/show?id=95ea39e304e' target=_blank style='color:#2F92EE;'>#呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39730, encryptionId=95ea39e304e, topicName=呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=02a536676444, createdName=bbwznl, createdTime=Mon Feb 15 00:04:14 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989159, encodeId=7a07198915982, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 03 12:04:14 CST 2020, time=2020-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885470, encodeId=d9f88854e0f5, content=可以做个研究, 打呼和糖尿病的关系,或者和心脏病的关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:15:08 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811062, encodeId=f182811062d4, content=👍🏻, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 16:25:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810860, encodeId=ef318108607c, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:59 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810859, encodeId=279681085948, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810858, encodeId=d776810858c2, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:55 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345578, encodeId=55bb13455e863, content=<a href='/topic/show?id=41b2e2996be' target=_blank style='color:#2F92EE;'>#睡眠呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72996, encryptionId=41b2e2996be, topicName=睡眠呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQBvJI9WesEs5nl29JIJ7mAquShibzBHQmTeHHwZMDlIzc5qoQUhTJOpOwiaxYa9UcibrZviaM7dL7aQ/132, createdBy=35cb2500499, createdName=ms1343860338762272, createdTime=Wed Aug 19 07:04:14 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810007, encodeId=d02a81000ec9, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=dfe85411515, createdName=ms8000001618437429, createdTime=Tue Aug 18 10:16:41 CST 2020, time=2020-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043290, encodeId=764a10432905a, content=谢谢MedSci提供最新的威廉亚洲官网 , beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 17 19:04:14 CST 2020, time=2020-08-17, status=1, ipAttribution=)]
    2020-08-19 ms5000000741733160

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1754416, encodeId=6dc41e5441692, content=<a href='/topic/show?id=95ea39e304e' target=_blank style='color:#2F92EE;'>#呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39730, encryptionId=95ea39e304e, topicName=呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=02a536676444, createdName=bbwznl, createdTime=Mon Feb 15 00:04:14 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1989159, encodeId=7a07198915982, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Tue Nov 03 12:04:14 CST 2020, time=2020-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=885470, encodeId=d9f88854e0f5, content=可以做个研究, 打呼和糖尿病的关系,或者和心脏病的关系, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b58d5402080, createdName=咻凡, createdTime=Tue Sep 15 14:15:08 CST 2020, time=2020-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=811062, encodeId=f182811062d4, content=👍🏻, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 16:25:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810860, encodeId=ef318108607c, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:59 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810859, encodeId=279681085948, content=👍, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:57 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810858, encodeId=d776810858c2, content=!, beContent=null, objectType=article, channel=null, level=null, likeNumber=108, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=25e55411955, createdName=ms5000000741733160, createdTime=Wed Aug 19 15:57:55 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1345578, encodeId=55bb13455e863, content=<a href='/topic/show?id=41b2e2996be' target=_blank style='color:#2F92EE;'>#睡眠呼吸障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72996, encryptionId=41b2e2996be, topicName=睡眠呼吸障碍)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKQBvJI9WesEs5nl29JIJ7mAquShibzBHQmTeHHwZMDlIzc5qoQUhTJOpOwiaxYa9UcibrZviaM7dL7aQ/132, createdBy=35cb2500499, createdName=ms1343860338762272, createdTime=Wed Aug 19 07:04:14 CST 2020, time=2020-08-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=810007, encodeId=d02a81000ec9, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=dfe85411515, createdName=ms8000001618437429, createdTime=Tue Aug 18 10:16:41 CST 2020, time=2020-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043290, encodeId=764a10432905a, content=谢谢MedSci提供最新的威廉亚洲官网 , beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 17 19:04:14 CST 2020, time=2020-08-17, status=1, ipAttribution=)]
    2020-08-19 ms5000000741733160

    👍

    0

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    2020-08-19 ms5000000741733160

    0

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    2020-08-18 ms8000001618437429

    0

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    2020-08-17 misszhang

    谢谢MedSci提供最新的威廉亚洲官网

    0

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