J Autism Dev Disord:无麸质饮食并不能改善自闭症儿童的功能行为

2020-08-05 MedSci原创 MedSci原创

本研究旨在确定无麸质饮食(GFD)与含麸质饮食(GD)相比是否会影响自闭症谱系障碍(ASD)儿童的功能。

本研究旨在确定无麸质饮食(GFD)与含麸质饮食(GD)相比是否会影响自闭症谱系障碍(ASD)儿童的功能。

 

采用随机、对照、单盲试验设计,纳入66名自闭症谱系障碍儿童(36-69个月),智商在正常范围内(>70),入组前至少服用GFD 8周。在8周的GFD运行期后,GFD组继续这种饮食,GD组每天至少食用一顿含有麸质的正常膳食,持续6个月。

 

结果显示,干预后,各组之间在自闭症症状、适应不良行为或智力方面没有差异。GFD与GD相比,对ASD儿童的功能没有影响。

 

原始出处:

 

Anna PiwowarczykAndrea Horvath, et al., Gluten-Free Diet in Children with Autism Spectrum Disorders: A Randomized, Controlled, Single-Blinded Trial. J Autism Dev Disord. 2020 Feb;50(2):482-490. doi: 10.1007/s10803-019-04266-9.

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    2021-01-24 cmsvly
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    2020-12-09 xuyu
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GetPortalCommentsPageByObjectIdResponse(id=806482, encodeId=60ca80648265, content=持续六个月,现在看到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Aug 06 11:11:39 CST 2020, time=2020-08-06, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1784427, encodeId=74401e84427ce, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sun Jan 24 17:00:36 CST 2021, time=2021-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071317, encodeId=f27f20e1317d3, content=<a href='/topic/show?id=b5d2300622' target=_blank style='color:#2F92EE;'>#autism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3006, encryptionId=b5d2300622, topicName=autism)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, 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  6. [GetPortalCommentsPageByObjectIdResponse(id=1784427, encodeId=74401e84427ce, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sun Jan 24 17:00:36 CST 2021, time=2021-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071317, encodeId=f27f20e1317d3, content=<a href='/topic/show?id=b5d2300622' target=_blank style='color:#2F92EE;'>#autism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3006, encryptionId=b5d2300622, topicName=autism)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, 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channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Wed Jun 16 02:00:36 CST 2021, time=2021-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527780, encodeId=63d1152e780c1, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Fri Aug 07 12:00:36 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556669, encodeId=155f155666905, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Fri Aug 07 12:00:36 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806768, encodeId=afb1806e68d4, content=样本量小,时间短, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200806/3c50335371e24f6e842e700c1a028737/f7c95d06a08745a1af4b6dfa8a6255d0.jpg, createdBy=b9c25401118, createdName=柠檬罗勒1983, createdTime=Fri Aug 07 11:24:52 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806482, encodeId=60ca80648265, content=持续六个月,现在看到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Aug 06 11:11:39 CST 2020, time=2020-08-06, status=1, ipAttribution=)]
    2021-06-16 fzwish20000
  7. [GetPortalCommentsPageByObjectIdResponse(id=1784427, encodeId=74401e84427ce, content=<a href='/topic/show?id=a727600194' target=_blank style='color:#2F92EE;'>#Disord#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6001, encryptionId=a727600194, topicName=Disord)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aad0444, createdName=cmsvly, createdTime=Sun Jan 24 17:00:36 CST 2021, time=2021-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2071317, encodeId=f27f20e1317d3, content=<a href='/topic/show?id=b5d2300622' target=_blank style='color:#2F92EE;'>#autism#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3006, encryptionId=b5d2300622, topicName=autism)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8f5b299, 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channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5878, encryptionId=13b658e849, topicName=Dev)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bcaa382, createdName=fzwish20000, createdTime=Wed Jun 16 02:00:36 CST 2021, time=2021-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1527780, encodeId=63d1152e780c1, content=<a href='/topic/show?id=68b5863e5d2' target=_blank style='color:#2F92EE;'>#自闭#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86375, encryptionId=68b5863e5d2, topicName=自闭)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=159511872623, createdName=xiongke014, createdTime=Fri Aug 07 12:00:36 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556669, encodeId=155f155666905, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Fri Aug 07 12:00:36 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806768, encodeId=afb1806e68d4, content=样本量小,时间短, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200806/3c50335371e24f6e842e700c1a028737/f7c95d06a08745a1af4b6dfa8a6255d0.jpg, createdBy=b9c25401118, createdName=柠檬罗勒1983, createdTime=Fri Aug 07 11:24:52 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806482, encodeId=60ca80648265, content=持续六个月,现在看到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Aug 06 11:11:39 CST 2020, time=2020-08-06, status=1, ipAttribution=)]
    2020-08-07 xiongke014
  8. 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  9. 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href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Fri Aug 07 12:00:36 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806768, encodeId=afb1806e68d4, content=样本量小,时间短, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200806/3c50335371e24f6e842e700c1a028737/f7c95d06a08745a1af4b6dfa8a6255d0.jpg, createdBy=b9c25401118, createdName=柠檬罗勒1983, createdTime=Fri Aug 07 11:24:52 CST 2020, time=2020-08-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=806482, encodeId=60ca80648265, content=持续六个月,现在看到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Aug 06 11:11:39 CST 2020, time=2020-08-06, status=1, ipAttribution=)]
    2020-08-07 柠檬罗勒1983

    样本量小,时间短

    0

  10. 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GetPortalCommentsPageByObjectIdResponse(id=806482, encodeId=60ca80648265, content=持续六个月,现在看到了, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Thu Aug 06 11:11:39 CST 2020, time=2020-08-06, status=1, ipAttribution=)]
    2020-08-06 Jessica

    持续六个月,现在看到了

    0

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