Circulation:重症新冠肺炎患者的心肌损伤风险及相关临床因素

2021-02-14 MedSci原创 MedSci原创

新冠肺炎(COVID-19)心肌损伤的流行病学和临床意义仍未完全明确。本研究旨在确定与非COVID-19的急性呼吸窘迫综合征(ARDS)相比,COVID-19重症患者心肌损伤的发生率和预后。

新冠肺炎COVID-19)心肌损伤的流行病学和临床意义仍未完全明确。本研究旨在确定与非COVID-19的急性呼吸窘迫综合征(ARDS)相比,COVID-19重症患者心肌损伤的发生率和预后。

纳入2020年3月15日-6月11日在5家医院治疗的COVID-19患者,评估其肌钙蛋白水平。研究人员将其与来自ARDS心肌损伤队列研究的患者进行比较,并对与心肌损伤相关的住院死亡的主要结局进行生存分析。此外,我采用线性回归来确定与COVID-19心肌损伤相关的临床因素。

同肌钙蛋白水平患者预后

共纳入了243位COVID-19患者,其中51%的患者的肌钙蛋白水平高于正常上限,慢性肾病、乳酸、铁蛋白和纤维蛋白原均与心肌损伤相关。肌钙蛋白低于正常值上限的COVID-19患者的死亡率为22.7%,而肌钙蛋白水平高于正常值上限10倍的患者的死亡率高达61.5%(P<0.001)。经年龄、性别和多系统器官功能障碍校整后,心肌损伤与死亡率的相关性在统计学上没有显著意义。

COVID-19患者的存活曲线

与非COVID-19的ARDS患者相比,COVID-19患者年龄较大,肌酐水平较高,生命体征较差经调整后,与非COVID-19相关的ARDS相比,cCOVID-19相关的ARDS心肌损伤发生率更低(优势比 0.55 [95% CI, 0.36-0.84];P=0.005)。

综上,与传统ARDS类似,COVID-19重症患者的心肌损伤发生风险与基线共病、高龄和多系统脏器功能障碍有关。COVID-19心肌损伤的不良预后主要与多系统器官受累和危重疾病有关

原始出处:

Thomas S. Metkus, et al. Myocardial Injury in Severe COVID-19 Compared With Non–COVID-19 Acute Respiratory Distress Syndrome. Circulation. 2021;143:553–565

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
    2021-09-24 howi
  2. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
    2021-02-15 carrotlyl

    沾边covid好发文

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2007584, encodeId=5715200e584b5, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Sep 24 21:55:48 CST 2021, time=2021-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1310087, encodeId=1d6a131008e40, content=<a href='/topic/show?id=ddd95126e4e' target=_blank style='color:#2F92EE;'>#心肌损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51267, encryptionId=ddd95126e4e, topicName=心肌损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4723380, createdName=yangcx0915, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1398098, encodeId=ce001398098b3, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579683, encodeId=3f3e15e968315, content=<a href='/topic/show?id=490795953ed' target=_blank style='color:#2F92EE;'>#重症新冠肺炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95953, encryptionId=490795953ed, topicName=重症新冠肺炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9f4216549541, createdName=ms5439512287675881, createdTime=Tue Feb 16 08:55:48 CST 2021, time=2021-02-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=924655, encodeId=0e95924655a0, content=沾边covid好发文, beContent=null, objectType=article, channel=null, level=null, likeNumber=103, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210127/50a003c4097845e182c08afd64d8a509/bd766dfebe9c40e0bca2dae964601bdc.jpg, createdBy=22de5454917, createdName=carrotlyl, createdTime=Mon Feb 15 07:51:49 CST 2021, time=2021-02-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1029134, encodeId=49e91029134b0, content=新冠肺炎,疫情何时才能消失, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=公卫新人, createdTime=Sun Feb 14 20:55:48 CST 2021, time=2021-02-14, status=1, ipAttribution=)]
    2021-02-14 公卫新人

    新冠肺炎,疫情何时才能消失

    0

相关威廉亚洲官网

盘点:2020年1月Stroke文章精选

【盘点】2020年1月Stroke文章精选

Heart:急性冠脉综合征恢复期肌钙蛋白水平仍可预测患者死亡风险

高敏肌钙蛋白检测常用于急性冠脉综合征的诊断,但其在冠心病恢复期的作用尚不清楚。本研究的目的旨在研究急性冠状动脉综合征后一系列恢复期高敏心肌肌钙蛋白浓度的长期预后意义。在本次包含2140名急性冠脉综合征的前瞻性多中心观察研究中,williamhill asia 对1776名患者进行了心脏肌钙蛋白I水平的检测,主要终点事件是心血管死亡事件。发病后4个月的肌钙蛋白浓度在99%的患者中是可检测的(年龄67±12岁,男性占72%),有4

BMJ:肌钙蛋白、年龄与患者预后

研究认为,肌钙蛋白水平高于正常上限人群的死亡风险增加,且不受年龄的影响,特别是阳性患者在检测后前几周内集中死亡风险极高

Heart:合并症对急性心肌梗死患者肌钙蛋白峰值水平和死亡率的影响

在对AMI患者进行的这项全国性分析中,合并症严重影响了cTn峰值的全身浓度。无论cTn峰值水平如何,合并症都是死亡率的重要预测指标,在将cTn解释为诊断和预后生物标志物时,应将其考虑在内。

Circulation:1小时肌钙蛋白T对于疑诊急性冠脉综合征患者治疗的指导意义

高敏感性肌钙蛋白检测可早期鉴别心肌梗死。Derek P. Chew等人开展一多中心的临床试验,评估0/1小时高敏感心肌肌钙蛋白T(hs-cTnT)方案与0/3小时hs-cTnT方案指导急症怀疑急性冠脉综合征患者的医疗护理的优劣性。受试患者被随机分至0/1小时hs-cTnT方案(hs-cTnT<5 ng/L)或0/3小时hs-cTnT方案组(hs-cTnT≤29 ng/L)(标准臂)。30天主

J Interv Cardiol :心梗肌钙蛋白变化幅度有价值!

一项研究表明,对于ST段抬高型心肌梗死患者来说,急诊冠脉介入治疗后的心肌肌钙蛋白I(cTnI)水平峰值与入院时cTnI水平差值(△cTnI)越大,未来发生主要不良心血管事件的风险越高。