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下丘脑

2022-01-06 ANDs 网络

下丘脑
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下丘脑

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    2022-01-07 zhouqu_8

    #下丘脑#

    0

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    2022-01-07 xlwang2696

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    2022-01-07 xlwang2696

    #丘脑#

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JN：下丘脑中的白介素-6可以防止肥胖，并参与神经发生的调节。

在运动条件下产生的白介素-6 (IL-6)在下丘脑中起到减少肥胖相关炎症的作用，并起到对食物摄入和能量消耗的控制。在下丘脑中，IL-6的一些有益作用归因于它的神经诱导特性。

Nat Commun ： 张骏组揭示下丘脑orexin神经系统在REM睡眠稳定维持中的重要作用

下丘脑作为脑内重要的稳态中枢，在睡眠/觉醒周期调控中发挥举足轻重的作用在临床研究中早被注意到在orexin缺陷病人中，除觉醒维持障碍外，睡眠障碍尤其是REM睡眠行为障碍也时常发生，其神经机制到底为何？

Nat Commun：下丘脑炎症是如何参与糖尿病表型的？

在下丘脑中，稳健和经典的炎症激活已被发现可以导致疾病，如厌食症和糜烂。同样，在啮齿动物模型和人类中，下丘脑炎症对于饮食肥胖和相关代谢紊乱的发病机制十分重要。

Neurology：下丘脑错构瘤和多指（趾）畸形：Pallister-Hall综合征

服用卡马西平后癫痫得到很好控制，且患儿发育正常。脑电图正常。脑MRI可见下丘脑错构瘤（图2）。

Nature:冯国平/傅展燕/李寅青等揭开丘脑网状核的神秘面纱

当你全神贯注于某件事时，往往会对周围的一切充耳不闻或者熟视无睹。究竟williamhill asia 的大脑是靠什么生理机制来实现这样的功能呢？秘密就藏在丘脑网状核（TRN）中。

PNAS：下丘脑POMC神经元中E-Syt3在营养性肥胖的形成中起重要的作用

近年来，在发达国家和发展中国家，肥胖人口均快速增加。肥胖会导致或促进心脑血管疾病、2型糖尿病，以及非酒精性脂肪肝等疾病的发生，危害人类的健康，因此，研究肥胖形成的原因以开发新的治疗方法显得至关重要。