JAHA:外周动脉疾病患者血压越低,心血管风险越高

2019-03-08 不详 MedSci原创

在外周动脉疾病患者中,高血压是一个心血管疾病的危险因素,然而这类患者的理想血压尚不清楚。本研究的目的旨在评估外周动脉疾病患者收缩压(SBP)与心血管疾病的相关性。本研究纳入了2773名患者,根据血压分为SBP≤120 mm Hg, n=604; 121–140 mm Hg, n=1065; 和 >140 mm Hg, n=1104。多元回归分析后发现与SBP在121–140 mm Hg的患者

在外周动脉疾病患者中,高血压是一个血管疾病的危险因素,然而这类患者的理想血压尚不清楚。本研究的目的旨在评估外周动脉疾病患者收缩压(SBP)与血管疾病的相关性。

本研究纳入了2773名患者,根据血压分为SBP≤120 mm Hg, n=604; 121–140 mm Hg, n=1065; 和 >140 mm Hg, n=1104。多元回归分析后发现与SBP在121–140 mm Hg的患者相比,SBP ≤120 mm Hg的患者发生心血管疾病的风险更高(心梗、卒中和心源性死亡)(HR:1.36; 95% CI, 1.08–1.72; P=0.009),SBP >140 mm Hg 的风险也更高(HR:1.23 ;95% CI, 1.00–1.51; P=0.051)。

研究结果显示,对于外周动脉疾病患者,收缩压≤120 mm Hg的患者发生心血管疾病的风险反而更高。

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