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Neurology：卒中相关性血脑屏障渗漏一例

2021-12-15 ANDs 网络

缺血性卒中
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FLAIR序列上与卒中相关的蛛网膜下腔和眼部钆渗漏可能代表了血脑/眼屏障破坏。早期的一份报告描述了卒中后>1个月进行的MRI可见到PVS钆渗漏。类淋巴系统（glymphatic）（在脑脊液-间质液交换

74岁，男性，右侧分水岭梗死。

入院时钆增强MRI显示右侧分水岭梗死（下图）。肾功能正常。4小时后MRI显示同侧血管周围间隙（PVS）和蛛网膜下腔FLAIR高信号，可能与卒中相关性延迟性钆渗漏有关（图）。10天后的MRI显示蛛网膜下腔/血管周围异常完全消失（图）。

下图，入院MRI（钆注射 MRA）显示右侧梗死（A，DWI）和血管周围间隙（PVS）（B，T1加权成像；C，FLAIR）。（D–F）四小时后，MRI显示同侧蛛网膜下腔（箭头）和深部及皮质下PVS（箭头）FLAIR高信号，为钆渗漏所致。（G–I）10天后观察到蛛网膜下腔/血管周围FLAIR异常信号完全消失：

FLAIR序列上与卒中相关的蛛网膜下腔和眼部钆渗漏可能代表了血脑/眼屏障破坏。早期的一份报告描述了卒中后>1个月进行的MRI可见到PVS钆渗漏。类淋巴系统（glymphatic）（在脑脊液-间质液交换中发挥作用）可能参与了蛛网膜下腔和PVS中观察到的卒中相关性血脑屏障渗漏。

文献出处：

Perivascular and Subarachnoid Fluid-Attenuated Inversion Recovery Hyperintensities Related to Delayed Gadolinium Leakage After Stroke. Neurology. 2021 Nov 23;97(21):1000-1001. doi: 10.1212/WNL.0000000000012854. Epub 2021 Sep 23.

 

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    2022-06-16 shenxlcyp

    #相关性#

    0

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    2021-12-29 yinhl1978

    #Neurol#

    0

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    2021-12-19 小明4083

    学习

    0

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    2021-12-19 zhangying8788

    #血脑屏障#

    0

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    2021-12-18 ms6000000145764456

    学习

    0

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