Addiction:吸食大麻青少年易发精神病

2012-12-28 Addiction 新华社 李 雯

  荷兰研究人员在英国医学期刊《瘾》上报告说,青少年吸食大麻容易引发精神病症状。研究人员据此再次呼吁青少年远离大麻等毒品。   此前有研究显示,吸食大麻的青少年患精神病的风险,比从不吸食大麻的青少年高1倍。此次研究进一步证实了这个结论。   荷兰莱顿大学的研究人员收集了2120名本国青少年的资料,调查他们在14岁、16岁和19岁时是否吸食过大麻。研究人员同时向他们询问“注意力是否集中”、“是否

  荷兰研究人员在英国医学期刊《瘾》上报告说,青少年吸食大麻容易引发精神病症状。研究人员据此再次呼吁青少年远离大麻等毒品。

  此前有研究显示,吸食大麻的青少年患精神病的风险,比从不吸食大麻的青少年高1倍。此次研究进一步证实了这个结论。

  荷兰莱顿大学的研究人员收集了2120名本国青少年的资料,调查他们在14岁、16岁和19岁时是否吸食过大麻。研究人员同时向他们询问“注意力是否集中”、“是否感到孤独”、“是否出现幻觉”等问题,以探究其患上精神病的可能性。

  结果显示,约44%的受访者,即940人吸食过大麻。大麻与精神病之间的关系是双向的。有些人是先吸食大麻再患精神病,而有些人是先有精神病症状才去吸食大麻。

  研究人员举例说,如果某人在16岁时吸食过大麻,那么3年后其患精神病的可能性明显增高。假如某人在16岁时出现精神病症状却未就医,则其在此后3年内因“异常精神需求”吸食大麻的可能性相对更大。

  研究人员呼吁说,由于大麻会对青少年的大脑发育产生影响,学校、家庭、社会都应采取干预行动,让青少年远离大麻等毒品。


Canna-bis Use and Vulnerability for Psychosis in Early Adolescence - a TRAILS Study

Aims
To examine the direction of the longitudinal association between vulnerability for psychosis and Canna-bis use throughout adolescence.
Design
Cross-lagged path analysis was used to identify the temporal order of vulnerability for psychosis and Canna-bis use, while controlling for gender, family psychopathology, alcohol use and tobacco use.
Setting
A large prospective population study of Dutch adolescents [the TRacking Adolescents′ Individual Lives Survey (TRAILS) study].
Participants
A total of 2,120 adolescents with assessments at (mean) age 13.6, age 16.3 and age 19.1.
Measurements
Vulnerability for psychosis at the three assessment points was represented by latent factors derived from scores on three scales of the Youth Self Report and the Adult Self Report, i.e. Thought Problems, Social Problems and Attention Problems. Participants self- reported on Canna-bis use during the past year at all three waves.
Findings
Significant associations (r=.12-.23) were observed between psychosis vulnerability and Canna-bis use at all assessments. Also, Canna-bis use at age 16 predicted psychosis vulnerability at age 19 (z=2.6, p<.05). Furthermore, psychosis vulnerability at ages 13 (z=2.0, p<.05) and 16 (z=3.0, p<.05) predicted Canna-bis use at, respectively, ages 16 and 19.
Conclusions
Canna-bis use predicts psychosis vulnerability in adolescents, and vice versa which suggests that there is a bi-directional causal association between the two.

    

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    2013-03-30 liuquan
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    2012-12-30 kcb069

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