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EJCTS发表上海儿童医学中心关于先天性气管狭窄迄今最大样本的临床研究成果

2022-06-15 上海儿童医学中心 上海儿童医学中心

先天性气管狭窄
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先天性气管狭窄（congenital tracheal stenosis，CTS）是危及婴幼儿生命安全的一种复杂先天性疾病，它曾一度被认为是婴幼儿心胸外科领域的禁区。

先天性气管狭窄（congenital tracheal stenosis，CTS）是危及婴幼儿生命安全的一种复杂先天性疾病，它曾一度被认为是婴幼儿心胸外科领域的禁区。由于其自然发病率低、异常解剖及病理结构复杂、手术难度大等特点使该疾病的治疗成为世界各医疗中心心胸外科医生的一大挑战。
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近日，国家儿童医学中心（上海）、上海交通大学医学院附属上海儿童医学中心心胸外科陆兆辉团队在国际权威期刊《European Journal of Cardio-Thoracic Surgery》发表题为“Surgical management of long-segment congenital tracheal stenosis with tracheobronchial malacia（长段先天性气管狭窄合并气管支气管软化的外科管理策略）”的临床研究成果。
研究团队对2010.01-2020.12上海儿童医学中心11年间收治的424例先天性气管狭窄患儿中的216例长段先天性气管狭窄患儿进行回顾性分析。研究结果表明，滑片吻合术过程中通过气管悬吊等技术可以获得更具支撑性和稳定性的气管隆突，因而有利于减少患儿术后呼吸机使用时间、重症监护时间及总体死亡率，对于改善滑片吻合术的预后具有重要意义。
 
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来自西班牙康普顿斯大学附属医院儿外科和儿童气道中心的J. L. Anton-Pacheco教授发表了对于该项研究的同行评论，他认为上海儿童医学中心是世界范围内最大的先天性气管狭窄儿童诊疗中心，并且高度肯定了王顺民主任提出的“better carina, better slide”的气管重建的理论。
上海儿童医学中心心脏中心徐志伟教授从2007年开始探索先天性气管狭窄的外科治疗方案，目前该团队已经完成500余例先天性气管狭窄患者的外科治疗，手术成功率从治疗开展初期的12.5%降至目前的几近“零死亡率”。陆兆辉教授、王顺民教授作为团队成员，近年来陆续在美国心胸外科年鉴（ATS）、美国胸心血管外科杂志（JTCVS）等专业权威期刊发表先天性气管狭窄治疗相关创新性论著。本论著为进一步提高滑片吻合术纠治长段先天性气管狭窄合并气管支气管软化的手术效果提供了全新的方案。
作者信息：本论文第一作者为上海儿童医学中心心胸外科研究生温皖豫，参与作者为上海儿童医学中心心胸外科杜欣为医生，朱丽敏主任，王顺民主任，徐志伟教授，通讯作者为心胸外科陆兆辉主任。

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    2022-08-02 xiongliangxl

    #研究成果#

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    2022-10-06 3631173

    #儿童医学中心#

    0

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    2022-12-20 fanweitanzhen

    #临床研究成果#

    0

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    2022-06-22 ms4000001015868584

    学习

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1898560, encodeId=5467189856051, content=<a href='/topic/show?id=0bdfe3394a4' target=_blank style='color:#2F92EE;'>#研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73394, encryptionId=0bdfe3394a4, topicName=研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84fb152, createdName=xiongliangxl, createdTime=Tue Aug 02 20:06:07 CST 2022, time=2022-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2046314, encodeId=1569204631426, content=<a href='/topic/show?id=6205282057e' target=_blank style='color:#2F92EE;'>#儿童医学中心#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28205, encryptionId=6205282057e, topicName=儿童医学中心)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Thu Oct 06 03:06:07 CST 2022, time=2022-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797531, encodeId=60811e97531b5, content=<a href='/topic/show?id=fdb722932e7' target=_blank style='color:#2F92EE;'>#临床研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22932, encryptionId=fdb722932e7, topicName=临床研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80ca273, createdName=fanweitanzhen, createdTime=Tue Dec 20 23:06:07 CST 2022, time=2022-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1227905, encodeId=1847122e90556, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1148099480, createdName=ms4000001015868584, createdTime=Wed Jun 22 08:44:12 CST 2022, time=2022-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1669489, encodeId=ca70166948980, content=<a href='/topic/show?id=9d7b620395d' target=_blank style='color:#2F92EE;'>#样本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62039, encryptionId=9d7b620395d, topicName=样本)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f33226554040, createdName=zhzhxiang, createdTime=Mon Feb 27 00:06:07 CST 2023, time=2023-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369593, encodeId=dd351369593fa, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461978, encodeId=d3c814619e894, content=<a href='/topic/show?id=10bf5438bc' target=_blank style='color:#2F92EE;'>#CTS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5438, encryptionId=10bf5438bc, topicName=CTS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=)]
    2023-02-27 zhzhxiang

    #样本#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1898560, encodeId=5467189856051, content=<a href='/topic/show?id=0bdfe3394a4' target=_blank style='color:#2F92EE;'>#研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73394, encryptionId=0bdfe3394a4, topicName=研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84fb152, createdName=xiongliangxl, createdTime=Tue Aug 02 20:06:07 CST 2022, time=2022-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2046314, encodeId=1569204631426, content=<a href='/topic/show?id=6205282057e' target=_blank style='color:#2F92EE;'>#儿童医学中心#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28205, encryptionId=6205282057e, topicName=儿童医学中心)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Thu Oct 06 03:06:07 CST 2022, time=2022-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797531, encodeId=60811e97531b5, content=<a href='/topic/show?id=fdb722932e7' target=_blank style='color:#2F92EE;'>#临床研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22932, encryptionId=fdb722932e7, topicName=临床研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80ca273, createdName=fanweitanzhen, createdTime=Tue Dec 20 23:06:07 CST 2022, time=2022-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1227905, encodeId=1847122e90556, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1148099480, createdName=ms4000001015868584, createdTime=Wed Jun 22 08:44:12 CST 2022, time=2022-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1669489, encodeId=ca70166948980, content=<a href='/topic/show?id=9d7b620395d' target=_blank style='color:#2F92EE;'>#样本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62039, encryptionId=9d7b620395d, topicName=样本)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f33226554040, createdName=zhzhxiang, createdTime=Mon Feb 27 00:06:07 CST 2023, time=2023-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369593, encodeId=dd351369593fa, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461978, encodeId=d3c814619e894, content=<a href='/topic/show?id=10bf5438bc' target=_blank style='color:#2F92EE;'>#CTS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5438, encryptionId=10bf5438bc, topicName=CTS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=)]
    2022-06-17 huirong

    #先天性#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1898560, encodeId=5467189856051, content=<a href='/topic/show?id=0bdfe3394a4' target=_blank style='color:#2F92EE;'>#研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73394, encryptionId=0bdfe3394a4, topicName=研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84fb152, createdName=xiongliangxl, createdTime=Tue Aug 02 20:06:07 CST 2022, time=2022-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2046314, encodeId=1569204631426, content=<a href='/topic/show?id=6205282057e' target=_blank style='color:#2F92EE;'>#儿童医学中心#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28205, encryptionId=6205282057e, topicName=儿童医学中心)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Thu Oct 06 03:06:07 CST 2022, time=2022-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797531, encodeId=60811e97531b5, content=<a href='/topic/show?id=fdb722932e7' target=_blank style='color:#2F92EE;'>#临床研究成果#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22932, encryptionId=fdb722932e7, topicName=临床研究成果)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=80ca273, createdName=fanweitanzhen, createdTime=Tue Dec 20 23:06:07 CST 2022, time=2022-12-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1227905, encodeId=1847122e90556, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d1148099480, createdName=ms4000001015868584, createdTime=Wed Jun 22 08:44:12 CST 2022, time=2022-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1669489, encodeId=ca70166948980, content=<a href='/topic/show?id=9d7b620395d' target=_blank style='color:#2F92EE;'>#样本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62039, encryptionId=9d7b620395d, topicName=样本)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f33226554040, createdName=zhzhxiang, createdTime=Mon Feb 27 00:06:07 CST 2023, time=2023-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1369593, encodeId=dd351369593fa, content=<a href='/topic/show?id=bc9f28589d0' target=_blank style='color:#2F92EE;'>#先天性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28589, encryptionId=bc9f28589d0, topicName=先天性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a435298, createdName=huirong, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1461978, encodeId=d3c814619e894, content=<a href='/topic/show?id=10bf5438bc' target=_blank style='color:#2F92EE;'>#CTS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5438, encryptionId=10bf5438bc, topicName=CTS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 17 01:06:07 CST 2022, time=2022-06-17, status=1, ipAttribution=)]
    2022-06-17 docwu2019

    #CTS#

    0