Stroke:危重病相关的脑微出血有啥特征?

2017-02-25 xing.T MedSci原创

在该研究中,研究人员描述了重大疾病患者大脑白质发生了一种独特的微出血现象。尽管这些患者大脑微出血的具体原因尚不清楚,但其发病机制可能涉及低氧血症,因为这些患者的脑部微出血与高厡暴露脑部微出血患者所描述的相类似。

引起脑微出血(点状出血)的众多原因中最为被人知晓了解的还是脑淀粉样血管病和慢性高血压。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员报告了12例在脑白质中出现临床和影像学独特的微出血现象。

在这个研究中,研究人员于2004年至2014年期间通过大学健康网络(多伦多,加拿大)对该研究的这些患者进行了评估。

该研究的参与者年龄中位数为40岁(变化范围为27-63岁),其中有7例患者为女性。所有患者在入住重症监护室之后立即或入住期间进行了脑磁共振成像检查。所有患者均出现呼吸衰竭,12例研究参与者中的11例患者接受机械通气治疗,另外,其中3例患者接受体外生命支持治疗。对12例患者进行磁共振成像检查均发现了患者存在广泛的出血、弥漫性地累及皮层白质、胼胝体,但并不累及大脑皮质、深部和脑室周围白质、基底节以及丘脑。一些患者也有内囊或后颅窝受累。

在该研究中,研究人员描述了重大疾病患者大脑白质发生了一种独特的微出血现象。尽管这些患者大脑微出血的具体原因尚不清楚,但其发病机制可能涉及低氧血症,因为这些患者的脑部微出血与高厡暴露脑部微出血患者所描述的相类似。         

原始出处:

Evgenia M. Fanou, et al. Critical Illness–Associated Cerebral Microbleeds.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.116.016289

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    2017-03-01 1e10c84am36(暂无匿称)

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