J Urol:勃起功能障碍是前列腺活检的暂时性并发症:系统性回顾和元分析

2020-10-27 AlexYang MedSci原创

由于现有文献中关于勃起功能障碍(ED)与前列腺活检的相关性并不一致,最近,有研究人员对前列腺活检后6个月内的男性性功能障碍进行系统回顾和元分析。

由于现有文献中关于勃起功能障碍(ED)与前列腺活检的相关性并不一致,最近,有研究人员对前列腺活检后6个月内的男性性功能障碍进行系统回顾和元分析。

研究人员对四个数据库[MEDLINE(通过PubMed)、Embase(通过Ovid)、Web of Science和The Cochrane Library]进行了系统性文献检索,并纳入了因怀疑前列腺癌而接受经直肠(TRUS)或经会阴(TPBx)前列腺活检所有年龄组男性的性功能障碍的研究,并包括了在活检前和活检后1、3或6个月进行国际勃起功能指数5(IIEF-5)评分的研究。研究人员还进行了一项比较患者的基线IIEF-5和活检后IIEF-5影响效果大小的元分析。研究人员最终确定了9项符合纳入标准的研究。研究发现,其中6项研究检查了TRUS,2项研究检查了TPBx,1项研究同时检查了TRUS和TPBx。在活检后1个月时,平均IIEF-5下降约2.2点(-0.43,p=0.002)。然而,在活检后3个月和6个月时,与基线相比没有差异(影响大小=-0.08,p=0.52,影响大小=-0.11,p=0.18)。探索性的亚组分析调查了3个月时的TRUS,结果显示IIEF-5平均得分与基线相比有统计学意义上的显著降低(p=0.047),即IIEF-5下降了约1.25分。

最后,研究人员指出,前列腺活检确实会在活检后1个月导致IIEF-5平均得分轻度、短暂的下降。然而,这种情况在平均3个月时就会消失,且在活检后6个月时,平均IIEF-5将保持在基线上。

原始出处:

J Fainberg , C D Gaffney , H Pierce et al. Erectile Dysfunction is a Transient Complication of Prostate Biopsy: A Systematic Review and Metanalysis. J Urol. Oct 2020

 

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    2021-08-01 丁鹏鹏
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    2020-12-14 habb
  6. [GetPortalCommentsPageByObjectIdResponse(id=1758292, encodeId=c6d51e5829273, content=<a href='/topic/show?id=84ba49031f9' target=_blank style='color:#2F92EE;'>#并发#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49031, encryptionId=84ba49031f9, topicName=并发)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a27e37327108, createdName=丁鹏鹏, createdTime=Sun Aug 01 16:16:27 CST 2021, time=2021-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2017251, encodeId=c8b0201e251ff, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Fri Nov 27 22:16:27 CST 2020, time=2020-11-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1905852, encodeId=0c1a1905852e4, content=<a href='/topic/show?id=8f2f28546b3' target=_blank style='color:#2F92EE;'>#元分析#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28546, encryptionId=8f2f28546b3, topicName=元分析)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b79433, createdName=jiangjun073, createdTime=Fri Apr 09 16:16:27 CST 2021, time=2021-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2046044, encodeId=85f32046044d3, content=<a href='/topic/show?id=e5713251390' target=_blank style='color:#2F92EE;'>#前列腺活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32513, encryptionId=e5713251390, topicName=前列腺活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4ba8129, createdName=zhzhxiang, createdTime=Tue Nov 03 04:16:27 CST 2020, time=2020-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1771202, encodeId=966b1e7120206, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Mon Dec 14 20:16:27 CST 2020, time=2020-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=895575, encodeId=f7948955e58d, content=阅读谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Fri Oct 30 07:13:08 CST 2020, time=2020-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1278211, encodeId=de5e12e821146, content=<a href='/topic/show?id=d34e6523544' target=_blank style='color:#2F92EE;'>#活检#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65235, encryptionId=d34e6523544, topicName=活检)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Thu Oct 29 14:16:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421338, encodeId=f01e142133897, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Thu Oct 29 14:16:27 CST 2020, time=2020-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502775, encodeId=64011502e754c, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Thu Oct 29 14:16:27 CST 2020, time=2020-10-29, status=1, ipAttribution=)]
    2020-10-30 刘煜

    阅读谢谢分享

    0

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    2020-10-29 smlt2008
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