Liver Int:锻炼预防超重、肥胖患者发生肝硬化

2017-08-30 MedSci MedSci原创

适度的锻炼可以防止肥胖和超重成年人发生肝硬化。运动时间超过推荐的150分钟/周,获益更多。

超重的肝病患者中锻炼改善了肝酶、胰岛素水平和生活质量。然而,锻炼预防肝硬化的证据还不确凿。因此,开展了一项有关运动对肥胖和超重成年人肝硬化影响的研究。

研究者使用2012年成人预防医疗服务数据集进行评估,并使用国家健康保险研究数据库确定肝硬化。所有参与者年龄≥40岁。采用logistic回归估计肝硬化的优势比。

研究结果表明1586例超重和1525例肥胖成人被确诊为肝硬化。每周锻炼时间超过150分钟对肥胖男性和女性的肝硬化有明显的保护作用。然而,每周锻炼时间少于150分钟仅仅对肥胖男性有保护作用。每周锻炼时间超过150分钟,肥胖男性、肥胖女性肝硬化的优势比分别为0.71(95%可信区间:0.584-0.841)、0.736(95%可信区间:0.562-0.964)。超重男性和女性调整后的优势比分别为0.734(95%可信区间:0.622 - 0.866)和0.503(95%可信区间:0.37-0.684)。每周锻炼时间少于150分钟,超重、肥胖男性优势比分别为0.879 (95%可信区间:0.788-0.980)、0.874 (95%可信区间:0.782-0.977);超重、肥胖女性优势比分别为0.918 (95%可信区间:0.778-1.083)、0.916 (95%可信区间:0.780-1.075)。

适度的锻炼可以防止肥胖和超重成年人发生肝硬化。运动时间超过推荐的150分钟/周,获益更多。

原始出处:

Jan CF, Nfor ON, Huang JY, et al. Exercise Might Prevent Liver Cirrhosis in Overweight and Obese Adults. Liver Int, 2017, Aug 19. doi: 10.1111/liv.13553.

本文系williamhill asia 医学(MedSci)原创编译整理,转载需授权

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-15 虈亣靌

    未来的发展前景广阔

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-02 虈亣靌

    好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛.

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-02 flysky120

    肥胖带来的疾病太多了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1950976, encodeId=db6619509e600, content=<a href='/topic/show?id=72078190803' target=_blank style='color:#2F92EE;'>#肥胖患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81908, encryptionId=72078190803, topicName=肥胖患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28b7142, createdName=liuquan, createdTime=Wed Sep 27 04:02:00 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244388, encodeId=f6be24438807, content=未来的发展前景广阔, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 15 20:45:28 CST 2017, time=2017-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239735, encodeId=8ffb239e3516, content=好文.值得点赞!认真学习了.把经验应用于实践.为患者解除病痛., beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Sep 02 13:43:45 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239728, encodeId=609b239e2810, content=肥胖带来的疾病太多了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sat Sep 02 13:02:31 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=239154, encodeId=2b8b2391543f, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Sep 01 00:32:07 CST 2017, time=2017-09-01, status=1, ipAttribution=)]
    2017-09-01 yfjms

    学习了

    0

相关威廉亚洲官网

Transla Psy:研究发现老年人锻炼身体可以预防痴呆!

许多研究表明,身体锻炼似乎有利于预防老年人的认知障碍和痴呆。现在,法兰克福歌德大学的研究人员已经在全球首例研究中探讨了运动如何影响脑部代谢。

J Bone Miner Res:不锻炼,连骨头也会长脂肪

锻炼减的不仅仅是你肚子上的肉。近日,一篇发表于Journal of Bone and Mineral Research上的小鼠研究表明,它还能改善骨骼厚度,提升骨质,甚至……减少骨头内的脂肪。没错,你的骨髓里也有脂肪。这项研究发现,运动——即跑步——能够促使肥胖和苗条的小鼠骨髓中脂肪细胞体积减少。不过,只有肥胖小鼠骨骼中的脂肪细胞的数量出现显着下降。“锻炼可以强化骨骼,这是众所周知的。”本研究带头

Inter J Rheu Dis:正确的运动对缓解关节疼痛很重要

据5月25日在线发表于International Journal of Rheumatic Diseases 杂志上的研究称,股四头肌等长收缩的锻炼方法是一种有效的缓解膝关节骨性关节炎(OA)疼痛的方法。

减少卡路里+锻炼增强老年人的肌肉功能

改善肌肉性能始于更好的线粒体功能。佛罗里达州奥兰多市的研究人员称,体重超标的老年人可以通过锻炼和减少热量摄入的减肥计划来改善肌肉功能。今天,他们在美国生理学学会的生理生物能量学上展示了他们的发现:从线粒体的基础研究到临床应用。研究人员对三组肥胖老年人(平均年龄70岁)进行了六个月的研究:一组遵循低卡路里饮食来减肥。第二组将热量限制与监督锻炼计划结合起来。对照组参加了健康教育课程,但没有遵循任何特定

Liver Int:在瑞士,戊型肝炎病毒是引起急性肝炎的原因

基于分子生物学的诊断显示戊型肝炎病毒是瑞士急性肝炎的相关病因。中老男性是发病的主要人群。在急性肝炎和神经痛性肌萎缩症的诊断治疗中应尽早检测HEV,这是HEV基因3型感染的典型肝外表现。

Diabetes Care:锻炼可以改善糖尿病患者心脏功能!

根据1月在芝加哥糖尿病护理中发表的一项研究,对于患有1型糖尿病的青少年,20周的运动训练干预与改善的有氧能力和中风发作率有关。