Heart:先心病患儿的很大摄氧量明显低于正常儿童

2018-06-03 MedSci MedSci原创

本研究的目的旨在评估先天性心脏病患儿的心肺功能与正常健康同龄儿童之间的差异,并寻找与最大摄氧量(VO2max)相关的临床特征。本次多中心横断面研究纳入了798名儿童(496名先心病患儿和302名正常儿童),并对其进行了完整的心肺功能测试(CPET)。分析结果显示,先心病组和对照组的平均VO2max预测值分别为93%±20%和107%±17%,先心病患儿的VO2max要明显更低(37.8±0.3vs

本研究的目的旨在评估先天性心脏病患儿的心肺功能与正常健康同龄儿童之间的差异,并寻找与最大摄氧量(VO2max)相关的临床特征。

本次多中心横断面研究纳入了798名儿童(496名先心病患儿和302名正常儿童),并对其进行了完整的心肺功能测试(CPET)。分析结果显示,先心病组和对照组的平均VO2max预测值分别为93%±20%和107%±17%,先心病患儿的VO2max要明显更低(37.8±0.3vs 42.6±0.4?mL/kg/min, P<0.0001),并且VO2max每年的下降值在先心病组中也明显更高。此外,与先心病患儿最大摄氧量相关的因素有体重指数、通气无氧阈值、女性、限制性通气障碍、右心室收缩高压、三尖瓣反流、心脏导管或手术步骤的数量以及基因的异常。

研究结果显示,先天性心脏病患儿的最大摄氧量要明显低于正常同龄儿童。

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    2018-06-05 ssnine
  2. [GetPortalCommentsPageByObjectIdResponse(id=1311479, encodeId=fd8c13114e947, content=<a href='/topic/show?id=a12628e0852' target=_blank style='color:#2F92EE;'>#先心病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28708, encryptionId=a12628e0852, topicName=先心病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356810, encodeId=438313568103d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562911, encodeId=b8b1156291148, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321205, encodeId=4457321205d4, content=学习了.谢谢作者分享!学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Sun Jun 03 20:53:23 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321203, encodeId=ac3332120369, content=陈v该好好还好还好哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Sun Jun 03 20:32:29 CST 2018, time=2018-06-03, status=1, ipAttribution=)]
    2018-06-05 zhaojie88
  3. [GetPortalCommentsPageByObjectIdResponse(id=1311479, encodeId=fd8c13114e947, content=<a href='/topic/show?id=a12628e0852' target=_blank style='color:#2F92EE;'>#先心病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28708, encryptionId=a12628e0852, topicName=先心病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=25c8396, createdName=ssnine, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356810, encodeId=438313568103d, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562911, encodeId=b8b1156291148, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Tue Jun 05 11:18:00 CST 2018, time=2018-06-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321205, encodeId=4457321205d4, content=学习了.谢谢作者分享!学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=121, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3xJXLtMtt5B40XXuPjn9xn1rBhrM6fHLkX1hI86ZoWoPJkgDkZuJNKkBfBHOcRd1fAdezg7JlHNOokohdAp3WkI/0, createdBy=32c81964262, createdName=1e145228m78(暂无匿称), createdTime=Sun Jun 03 20:53:23 CST 2018, time=2018-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321203, encodeId=ac3332120369, content=陈v该好好还好还好哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b0171930782, createdName=为你把脉, createdTime=Sun Jun 03 20:32:29 CST 2018, time=2018-06-03, status=1, ipAttribution=)]
    2018-06-05 slcumt
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    2018-06-03 1e145228m78(暂无匿称)

    学习了.谢谢作者分享!学习了.谢谢作者分享!

    0

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    2018-06-03 为你把脉

    陈v该好好还好还好哈

    0

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