Sci Rep:牙周炎的发生与血清IgE的水平是否相关?

2017-06-18 MedSci MedSci原创

牙周炎是影响牙齿支持组织(牙周组织)的炎症性疾病,已知牙周炎与慢性疾病,如心血管疾病、胰岛素抵抗等存在关联。然而,关于牙周炎和血清IgE之间的关联目前尚未清楚。 韩国的2010次全国健康和营养调查(KNHANES V-1)中共纳入了8958名参与者,其中年龄在19至64岁的1731名成年人测定了血清特异性IgE的水平,将其纳入研究分析。牙医检查了所有受试者的牙周状况。使用多元logisti

牙周炎是影响牙齿支持组织(牙周组织)的炎症性疾病,已知牙周炎与慢性疾病,如心血管疾病、胰岛素抵抗等存在关联。然而,关于牙周炎和血清IgE之间的关联目前尚未清楚。

韩国的2010次全国健康和营养调查(KNHANES V-1)中共纳入了8958名参与者,其中年龄在19至64岁的1731名成年人测定了血清特异性IgE的水平,将其纳入研究分析。牙医检查了所有受试者的牙周状况。使用多元logistic回归分析评价牙周炎与总IgE和对蟑螂和屋尘螨的特异性IgE关联的比值比。

结果显示,在男性中,总IgE的水平与牙周炎的存在呈正相关。蟑螂特异性IgE水平最高前1/3的参与者(T3,> 31.6 kU/L)牙周炎的发生风险显著升高(OR= 2.108;95% CI,1.233–3.606)。在女性中,总IgE的水平和牙周炎之间存在相反的关联(OR = 0.409;95% CI,0.200–0.839)。

本研究首次采用全国人群为基础的横断面健康检查研究,证实牙周炎与血清IgE的相关性。研究结果表明,韩国男性牙周炎的发生与蟑螂特异性IgE的水平呈正相关。

原始出处:

Mihee Hong,Jun-Beom Park, et al., Association between Cockroach-specific Immunoglobulin E and periodontitis in Korean male adults Based on Korean National Health and Nutrition Examination Survey. Sci Rep. 2017; 7: 46373. Published online 2017 Apr 12. doi:  10.1038/srep46373.

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    2017-06-20 zhenjiu124
  2. [GetPortalCommentsPageByObjectIdResponse(id=1426344, encodeId=c32e1426344ae, content=<a href='/topic/show?id=032b948ec5' target=_blank style='color:#2F92EE;'>#IgE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9487, encryptionId=032b948ec5, topicName=IgE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0cff4064659, createdName=zhenjiu124, createdTime=Tue Jun 20 03:31:00 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450529, encodeId=26ff14505291b, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jun 20 03:31:00 CST 2017, time=2017-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212380, encodeId=aabc212380dd, content=看看了解一下了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=90f31612316, createdName=xiaotaiyang1, createdTime=Sun Jun 18 16:28:12 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212313, encodeId=f11b2123131f, content=学习了,谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sun Jun 18 12:43:18 CST 2017, time=2017-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=212303, encodeId=467621230374, content=学习了,涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sun Jun 18 12:39:10 CST 2017, time=2017-06-18, status=1, ipAttribution=)]
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    2017-06-18 xiaotaiyang1

    看看了解一下了,谢谢分享

    0

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    2017-06-18 清风拂面

    学习了,谢谢分享

    0

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    2017-06-18 1ddf0692m34(暂无匿称)

    学习了,涨知识

    0