J Rheumatol:系统性硬化症中粪便钙卫蛋白水平升高与间质性肺病的关联

2018-11-17 xiangting MedSci原创

该研究证明了,ILD与SSc中的FC水平升高独立相关。

这项研究旨在评估系统性硬化症(SSc)中粪便钙卫蛋白(FC)与间质性肺病(ILD)的关联。

该研究纳入了129例门诊的SSc患者。收集关于疾病特征,特别是肺部受累的数据,并对FC进行测量。

ILD患者(35例,27.1%)的FC数值较高(p<0.001)。在多因素分析中,以下变量与ILD的风险升高相关:弥漫性疾病亚组、改良Rodnan皮肤评分较高、病程较长、严重程度评分较高、类固醇治疗和FC水平较高,然而憩室病具有保护作用。

该研究证明了,ILD与SSc中的FC水平升高独立相关。

原始出处:

Cristian Caimmi. Relationship Between Increased Fecal Calprotectin Levels and Interstitial Lung Disease in Systemic Sclerosis.  J Rheumatol. 15 November 2018.

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    2019-09-28 amy0559
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    2018-11-19 Homburg
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