J Rheumatol:手部骨关节炎加速的特征:来自骨关节炎创议的数据

2018-12-09 xiangting MedSci原创

手部可以出现加速OA,尤其是常用于捏和精细运动技能的手指。

这项研究旨在确定手关节是否会出现骨关节炎(OA)的一种加速形式,并对出现手部骨关节炎加速(AHOA)的个体进行表征。

研究人员对骨关节炎创议中有基线和48个月影像学手部骨关节炎(HOA)完整数据的3519名参与者进行了评估。一名阅片者使用改良Kellgren-Lawrence量表(KL)对优势手后前位片进行评分,另一名阅片者对是否存在中心或边缘糜烂进行评分。第三名阅片者读片并对OA以外的疾病征象进行标记。将AHOA定义为48个月时≥1个关节从基线时KL 0或1级进展到3或4级。

4年内1%的患者达到了AHOA定义:37只手有1个关节受累,1只手有2个关节受累。基线时与没有AHOA的患者相比,进展为AHOA的成年人更容易出现手部疼痛(37%vs 22%)、影像学HOA(71%vs 36%)、以及其他关节的中心(22%vs 7%)和边缘糜烂(11%vs 2%)。AHOA成年患者(中心35%,边缘5%)比不伴AHOA的患者(中心5%,边缘1%)在48个月内更容易发生新糜烂。加速OA的最常见部位是第二掌指关节和第一腕掌关节。

手部可以出现加速OA,尤其是常用于捏和精细运动技能的手指。

原始出处:

Julie E. Davis. Characteristics of Accelerated Hand Osteoarthritis: Data from the Osteoarthritis Initiative. J Rheumatol. 01 December 2018.

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    2019-10-08 lisa438
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    2018-12-11 lmm397

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