Am J Med:牙周袋深度和血糖也能影响慢性肾脏病的进展?

2016-11-11 MedSci MedSci原创

本研究调查牙周疾病患者,其牙周袋深度和高血糖对慢性肾脏病进展的影响。 研究纳入2831例牙周疾病患者,通过牙周袋深度对牙周病的严重程度分级。 在7621人年的随访中,牙周袋深度和HbA1C水平与慢性肾脏病进展风险的增加显著相关(牙周袋深度 >4.5 mm,aHR 3.1; 95% CI, 2.0-4.6;HbA1C >6.5%,aHR 2.5; 95% CI, 1.1-5.

本研究调查牙周疾病患者,其牙周袋深度和高血糖对慢性肾脏病进展的影响。

研究纳入2831例牙周疾病患者,通过牙周袋深度对牙周病的严重程度分级。

在7621人年的随访中,牙周袋深度和HbA1C水平与慢性肾脏病进展风险的增加显著相关(牙周袋深度 >4.5 mm,aHR 3.1; 95% CI, 2.0-4.6;HbA1C >6.5%,aHR 2.5; 95% CI, 1.1-5.4)。

牙周袋深度和HbA1C的相互作用对慢性肾脏病进展的影响也非常强(P <.01)。

牙周疾病患者如果有更高的牙周袋深度(>4.5 mm)和更高的HbA1C (>6.5%),其慢性肾脏病进展的风险最高(aHR 4.2; 95% CI, 1.7-6.8)。

如果牙周疾病患者的牙周袋深度≤3.8 mm,同时HbA1C ≤6%,其慢性肾脏病进展的风险最低。

结果发现,联合牙周袋深度和HbA1C可以作为牙周病患者慢性肾脏病进展的预测指标。考虑到牙周疾病和高血糖之间的相互作用,对患者进行牙周检查和优化血糖控制是必要的,以尽量减少肾功能恶化的风险。

原始出处:


Chang JF1, Yeh JC2, et al.Periodontal Pocket Depth, Hyperglycemia, and Progression of Chronic Kidney Disease: A Population-Based Longitudinal Study.Am J Med. 2016 Sep 9. pii: S0002-9343(16)30911-1. doi: 10.1016/j.amjmed.2016.08.024. [Epub ahead of print]

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    2017-02-08 1ddf0692m34(暂无匿称)

    大开眼界!

    0

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    2016-11-23 zhixue

    牙周病和全身疾病都有关系,只是还没重视起来

    0

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