Sci Rep:骨钙素在患有勃起功能障碍的中年男性中的潜在保护性作用研究

2018-05-09 AlexYang MedSci原创

与勃起功能障碍(ED)相似,骨钙素(OC)同样被认为与心血管疾病(CVD)相关;然而,OC在ED中的作用仍旧不清楚。最近,有研究人员基于2009年9月到12月之间的防城港地区的男性健康调查(FAMHES)计划数据进行了相关的研究。研究人员利用国际勃起功能指数(IIEF-5)评估了ED情况。研究发现,OC与轻度(未调整: OR=0.647; P=0.016)或者中度(未调整:OR=0.453; P=

与勃起功能障碍(ED)相似,骨钙素(OC)同样被认为与心血管疾病(CVD)相关;然而,OC在ED中的作用仍旧不清楚。

最近,有研究人员基于2009年9月到12月之间的防城港地区的男性健康调查(FAMHES)计划数据进行了相关的研究。研究人员利用国际勃起功能指数(IIEF-5)评估了ED情况。研究发现,OC与轻度(未调整: OR=0.647; P=0.016)或者中度(未调整:OR=0.453; P=0.007)ED相关。同时,更高水平的OC与ED更加明显的相关(未调整: OR=0.702; P=0.014)。当研究人员将参与者按照年龄分组,OC与ED的相关性只在那些40-49岁之间的人群中出现,甚至在多重调整后模型且患有中度(OR=0.255, P=0.044)或者重度(OR=0.065, P=0.005)ED的患者中同样有上述现象。另外,OC与ED的关系同时也与高水平的睾丸素水平、非肥胖、饮酒和非代谢综合症相关。

最后,研究人员指出,OC也许在患有中度到重度ED的中年(40-49岁)男性中具有保护性作用,尤其是在那些具有高水平睾丸素、非肥胖、饮酒和非代谢综合症的男性中。

原始出处:


本文系williamhill asia 医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“williamhill asia 医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于williamhill asia 医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“williamhill asia 医学”。其它来源的文章系转载文章,或“williamhill asia 号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与williamhill asia 联系,williamhill asia 将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1771145, encodeId=e0881e7114533, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Mon Dec 10 13:51:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421159, encodeId=0a5f1421159b0, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502724, encodeId=90e61502e247a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313905, encodeId=9b273139056b, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 22:00:00 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-12-10 habb
  2. [GetPortalCommentsPageByObjectIdResponse(id=1771145, encodeId=e0881e7114533, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Mon Dec 10 13:51:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421159, encodeId=0a5f1421159b0, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502724, encodeId=90e61502e247a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313905, encodeId=9b273139056b, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 22:00:00 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1771145, encodeId=e0881e7114533, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Mon Dec 10 13:51:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421159, encodeId=0a5f1421159b0, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502724, encodeId=90e61502e247a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313905, encodeId=9b273139056b, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 22:00:00 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1771145, encodeId=e0881e7114533, content=<a href='/topic/show?id=c1c6334227d' target=_blank style='color:#2F92EE;'>#勃起#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33422, encryptionId=c1c6334227d, topicName=勃起)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=78b838213583, createdName=habb, createdTime=Mon Dec 10 13:51:00 CST 2018, time=2018-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421159, encodeId=0a5f1421159b0, content=<a href='/topic/show?id=09d33294eb8' target=_blank style='color:#2F92EE;'>#功能障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32947, encryptionId=09d33294eb8, topicName=功能障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3493649807, createdName=naiwu78, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1502724, encodeId=90e61502e247a, content=<a href='/topic/show?id=bf0f3342395' target=_blank style='color:#2F92EE;'>#勃起功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33423, encryptionId=bf0f3342395, topicName=勃起功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e529549448, createdName=liuyiping, createdTime=Fri May 11 10:51:00 CST 2018, time=2018-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=313905, encodeId=9b273139056b, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6b0d1671629, createdName=1de11f7fm56(暂无匿称), createdTime=Thu May 10 22:00:00 CST 2018, time=2018-05-10, status=1, ipAttribution=)]
    2018-05-10 1de11f7fm56(暂无匿称)

    学习了.谢谢分享

    0

相关威廉亚洲官网

J Clin Periodontol:瑟瑟发抖!慢性牙周炎或可导致勃起功能障碍!

本研究旨在校正生物标志物和其他合并症后确定慢性牙周炎与勃起功能障碍之间的关系。纳入158名男性患者进行病例对照研究。根据国际勃起功能指数,80例勃起功能障碍患者,78例对照者。收集社会人口学资料并进行牙周检查。评估睾酮、血脂谱、C-反应蛋白和血糖参数。所有变量进行组间比较,并进行多因素logistic回归分析。结果显示,74%的病例诊断为慢性牙周炎。病例组探诊深度4-6 mm(p = 0.05)和

Int J Impot Res:阴茎勃起功能障碍病人中潜在的结核感染研究

关于在阴茎勃起功能障碍病人中潜在的结核感染(LTBI)流行度以及它通过慢性炎症诱导的动脉粥样硬化过程而对高等级ED的贡献方面的调查研究到目前为止还没有。最近,有研究人员确定了在阴茎勃起功能障碍病人群体中LTBI的频率,并且探索了LTBI对高等级ED的贡献情况。对所有的研究样本,研究人员进行了临床评估、成像研究和实验室调查。评估包括但不仅限于经阴囊超声、结核菌素皮试和QuantiFERON-TB G

糖尿病会让男人“硬不起来”?!

男性勃起功能障碍(ED),也称为阳萎,是指无法达到和维持勃起足够长的时间完成性交。

Int J Impot Res:肌生成抑制蛋白,一种纤维化因子和横纹肌群的主要抑制子,存在于阴茎和血管平滑肌中

肌生成抑制蛋白在平滑肌细胞(SMC)中存在于有条纹的肌纤维中(除了肌层细胞)中还未报道。最近,研究人员在小鼠中调查了是否肌生成抑制蛋白存在于阴茎的SMC中和血管壁中,如果存在,肌生成抑制蛋白是否转录表达并且与某几种形式的勃起功能障碍(ED)的海绵体SMC的缺失有关,研究人员对其进行了探究。研究人员利用免疫组化技术或者荧光技术和蛋白免疫印迹技术,在会阴横纹肌、阴茎海绵体的SMC、动脉和静脉以及主动脉

盘点:近期男性生殖健康相关研究进展一览

【1】Eur Urol:人类阴茎移植和排斥反应的间接体内疗法新模型:对勃起组织生理机能的影响阴茎移植是一种治疗阴茎组织受到严重损失的潜在治疗选择方法。但是人类阴茎移植排斥模型还缺乏。研究人员利用一种新的间接体内疗法混合淋巴细胞反应模型来评估排斥反应和免疫抑制反应对海绵组织的影响。研究材料为10位经历过阴茎假体手术的病人的海绵组织和外周血单个核细胞以及1位健康志愿者的外周血单个核细胞。研究人员为

Sci Rep:代谢综合征与勃起功能障碍有关!

代谢综合征(MetS)是勃起功能障碍(ED)的一个风险因子,但是潜在的机制仍旧不清楚。最近,有研究人员进行了旨在确定代谢综合征相关ED(MED)的潜在机制。研究人员对Sprague Dawley(SD)大鼠进行了为期6个月的高脂肪喂养,之后对其进行了代谢参数的评估,并且进行了阿朴吗啡测试来确定MED。另外,研究人员只对那些患有MED的大鼠进行为期4周的表皮生长因子(EGF)或者媒介物的阴茎注射,并