Hum Reprod Update:无排卵性PCOS患者不孕管理威廉亚洲博彩公司 推荐

2016-08-24 MedSci MedSci原创

美国生殖医学中心人员对提交给世卫组织(WHO)的询证威廉亚洲博彩公司 进行了总结,描述了威廉亚洲博彩公司 的方法,以综述的形式阐明了对女性多囊卵巢综合征(PCOS)导致的无排卵性不孕的管理。提供支持威廉亚洲博彩公司 的证据包括的合作过程:1.识别首要问题和关键结局,2.检索最新的证据和现有的威廉亚洲博彩公司 ,3.评估和综合证据,4.制定威廉亚洲博彩公司 草案达成在全球范围内相关人员的共识。每个威廉亚洲博彩公司 推荐都进行了质量评估,使用极低、低、中或高质量进行分级。综合证据后在

美国生殖医学中心人员对提交给世卫组织(WHO)的询证威廉亚洲博彩公司 进行了总结,描述了威廉亚洲博彩公司 的方法,以综述的形式阐明了对女性多囊卵巢综合征(PCOS)导致的无排卵性不孕的管理。

提供支持威廉亚洲博彩公司 的证据包括的合作过程:1.识别首要问题和关键结局,2.检索最新的证据和现有的威廉亚洲博彩公司 ,3.评估和综合证据,4.制定威廉亚洲博彩公司 草案达成在全球范围内相关人员的共识。每个威廉亚洲博彩公司 推荐都进行了质量评估,使用极低、低、中或高质量进行分级。

综合证据后在PCOS的定义基础上制定威廉亚洲博彩公司 推荐,包括高雄激素血症,月经周期调节和卵巢评估。涵盖了方法特征和伦理影响。

管理包括生活方式改变、肥胖手术、药物治疗(包括克罗米芬CC,芳香化酶抑制剂,二甲双胍和促性腺激素),以及腹腔镜手术。IVF视作PCOS患者排卵和妊娠的风险因素。

生活方式干预是肥胖患者的首要建议,很大程度上是基于整体的健康获益。
生活方式干预失败,BMI ≥35 kg/m2的患者可进行减肥手术。
谨慎实施和监管的药物诱导排卵可取得较好的累积妊娠率,遵循威廉亚洲博彩公司 推荐可最大限度的减少多胎妊娠。
CC是诱导排卵的一线治疗,来曲唑也可作为一线治疗。
二甲双胍单药对提高活产率益处有限。
无明显证据支持针灸或中药对改善PCOS有效。
生活方式干预诱导排卵失败,或有其他不孕因素的PCOS女性,在使用较安全GnRH拮抗剂方案中可进行IVF。
若使用GnRH激动剂方案,辅助使用二甲双胍可降低卵巢过度刺激综合征风险。
患者应被告知诱导排卵的潜在副作用和IVF对胎儿的影响,以及多胎妊娠风险。
肥胖可增加母胎妊娠期风险,应单独讨论。

这个威廉亚洲博彩公司 可适用于全球范围内无排卵性PCOS患者诱导排卵的安全管理。

原始出处:

Balen AH1, Morley LC2, Misso M3,et al,The management of anovulatory infertility in women with polycystic ovary syndrome: an analysis of the evidence to support the development of global WHO guidance,Hum Reprod Update. 2016 Aug 10. [Epub ahead of print]

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  4. 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  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:36:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105008, encodeId=a77a105008ac, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:36:00 CST 2016, time=2016-08-26, status=1, ipAttribution=)]
    2017-01-24 hxzhang
  6. 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createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:37:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105018, encodeId=01501050187f, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:37:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105006, encodeId=125e105006d6, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:36:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105008, encodeId=a77a105008ac, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Fri Aug 26 19:36:00 CST 2016, time=2016-08-26, status=1, ipAttribution=)]
    2016-09-27 ylzr123

    赞一个!好文章拜读了,认真学习了。

    0

  7. 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    2016-08-26 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  8. 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    2016-08-26 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  9. 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    2016-08-26 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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    2016-08-26 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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