JAAD:Ixekizumab 的长期疗效和安全性

2021-09-06 医路坦克 MedSci原创

Ixekizumab 是一种有效的中度至重度斑块状银屑病治疗方法，具有良好的安全性特征。ixekizumab 疗法适用于斑块状银屑病患者的长期治疗。

Ixekizumab 是一种有效的中度至重度斑块状银屑病治疗方法，具有良好的安全性特征。患者在264 周期间经历了持续的皮肤清除反应率和一致的安全性。总体而言，Ixekizumab 疗法适用于斑块状银屑病患者的长期治疗.

患者 (N=1346) 以 1:2:2:2 的比例随机接受皮下注射安慰剂、依那西普 50 毫克每周两次、IXE 毫克每 2 周 (Q2W) 或每 4 周 (Q4W) 在初始剂量 IXE 160 后毫克。在第 12 周，患者使用 IXEQ4W 给药进入长期延长 (LTE) 期，并可能在第 60 周后升级至 Q2W。报告了意向治疗人群的 IXEQ2W/Q4W 组的疗效。接受至少 1 剂 IXEQ2W/Q4W 的患者报告了安全性。

患者在第 264 周期间经历了持续的皮肤清除反应率和一致的安全性。总体而言，ixekizumab 疗法适用于斑块状银屑病患者的长期治疗。

文献来源：Blauvelt A, Lebwohl MG, Mabuchi T，Long-term efficacy and safety of ixekizumab: A 5-year analysis of the UNCOVER-3 randomized controlled trial.J Am Acad Dermatol 2021 Aug;85(2)

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2021-12-19 经常头晕

#疗效和安全性#

50 0
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2022-07-18 snf701207

#mAb#

57 0
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2021-09-08 snowpeakxu

#ixekizumab#

57 0
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2021-09-08 gjsgj

#长期疗效#

81 0
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2021-09-06 内科新手

谢谢williamhill asia 提供这么好的信息，学到很多

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