河北医大二医傅向华等发现,桡动脉介入治疗时桡动脉痉挛率达75%,硝酸甘油可有效缓解痉挛

2018-02-02 朱柳媛 中国循环杂志

桡动脉痉挛是经桡动脉冠脉介入术中常见的并发症,尤其在穿刺和导丝导管上行过程中容易出现,可引起穿刺失败、前臂疼痛、内膜损伤。据报道,桡动脉痉挛发生率可达20.0%~51.3%。


桡动脉痉挛是经桡动脉冠脉介入术中常见的并发症,尤其在穿刺和导丝导管上行过程中容易出现,可引起穿刺失败、前臂疼痛、内膜损伤。据报道,桡动脉痉挛发生率可达20.0%~51.3%。
 
河北医科大学第二医院心内科傅向华、毕希乐等人通过光学相干断层成像(OCT)检查发现,在经桡动脉行冠脉介入治疗的过程中,桡动脉痉挛发生率高达75%,而硝酸甘油这一扩血管药物可有效缓解桡动脉痉挛。
 
OCT显示,桡动脉痉挛时,痉挛血管与正常血管呈渐进式延续,可以清晰显示弥漫性和局限性血管痉挛。研究人员认为,这两种痉挛形式都是由重到轻的过渡形式。
 
作者指出,实际中术者常通过触觉感受导丝、导管上行的阻力和桡动脉搏动的强弱判断桡动脉痉挛很容易受个人主观因素影响,桡动脉痉挛在实际中被大大低估。
 
研究者强调,“桡动脉痉挛的预防胜于治疗。”他们指出,在无鞘保护区域
内的血管损伤应引起临床重视。目前桡动脉痉挛的预防包括穿刺前充分的麻醉、亲水涂层鞘管及血管扩张剂的应用。
 
在该研究中,他们向桡动脉内部注射硝酸甘油后,血管面积比平均增大约50%,血管中膜厚度也明显变薄,接近正常血管中膜。由于中膜平滑肌只是形态发生了变化,平滑肌的总量并没有实质改变,所以痉挛时和缓解后的血管中膜总面积并没有差异。
 
该研究纳入20例经桡动脉冠脉介入治疗术后行桡动脉OCT检查的患者,其中桡动脉痉挛占15例,桡动脉内膜撕裂1 例。

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    2018-02-04 apoenzyme
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    2018-02-03 老坛

    学习了

    0

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    2018-02-03 惠映实验室

    学习..谢谢分享.

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1309332, encodeId=a7771309332e8, content=<a href='/topic/show?id=9faae35400d' target=_blank style='color:#2F92EE;'>#硝酸甘油#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73540, encryptionId=9faae35400d, topicName=硝酸甘油)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Sun Feb 04 12:37:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1311754, encodeId=5cf11311e540d, content=<a href='/topic/show?id=624de11204a' target=_blank style='color:#2F92EE;'>#痉挛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71120, encryptionId=624de11204a, topicName=痉挛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7dc7399, createdName=apoenzyme, createdTime=Sun Feb 04 12:37:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1441100, encodeId=d1721441100cf, content=<a href='/topic/show?id=81a3623569c' target=_blank style='color:#2F92EE;'>#桡动脉#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62356, encryptionId=81a3623569c, topicName=桡动脉)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae384789560, createdName=12498aa2m63(暂无昵称), createdTime=Sun Feb 04 12:37:00 CST 2018, time=2018-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284777, encodeId=241a284e771a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIVRqj4iarZPMruOs51Vuiba4Sja9gGBQetbhlHEOYUEScQ2BQ4wSaItfuuJU7Z3U8UysINtNHSEGrw/0, createdBy=37592204366, createdName=老坛, createdTime=Sat Feb 03 17:10:26 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284586, encodeId=314f2845868b, content=学习..谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Feb 03 00:24:34 CST 2018, time=2018-02-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284566, encodeId=4ef8284566d3, content=不错的文章.值得拥有, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Fri Feb 02 23:28:26 CST 2018, time=2018-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=284552, encodeId=b67c28455220, content=桡动脉痉挛是经桡动脉冠脉介入术中常见的并发症.尤其在穿刺和导丝导管上行过程中容易出现.可引起穿刺失败.前臂疼痛.内膜损伤.据报道.桡动脉痉挛发生率可达20.0%~51.3%., beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Fri Feb 02 22:30:40 CST 2018, time=2018-02-02, status=1, ipAttribution=)]
    2018-02-02 1e1b8538m79(暂无匿称)

    不错的文章.值得拥有

    0

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    2018-02-02 有备才能无患

    桡动脉痉挛是经桡动脉冠脉介入术中常见的并发症.尤其在穿刺和导丝导管上行过程中容易出现.可引起穿刺失败.前臂疼痛.内膜损伤.据报道.桡动脉痉挛发生率可达20.0%~51.3%.

    0