ESPE 2015:身高越高的人患癌风险越大!

2015-10-04 MedSci MedSci原创

在西班牙巴塞罗那举行的第54届欧洲儿科内分泌学学会会议上,研究人员发表看法:越高的人患癌风险越大。 这项研究由斯德哥尔摩大学和卡罗林斯卡医学院的研究学者组成研究团队,他们对550万名年龄超过20岁的男性和女性1958年-2011年进行了追踪随访。所有的参与者在1938年-1991年间出生,他们的成年身高范围在100-225cm。  卡罗林斯卡医学院博士生Emelie Benyi博士领导了

在西班牙巴塞罗那举行的第54届欧洲儿科内分泌学学会会议(European Society for Paediatric Endocrinology Meeting)上,研究人员发表看法:越高的人患癌风险越大。 


这项研究由斯德哥尔摩大学和卡罗林斯卡医学院的研究学者组成研究团队,他们对550万名年龄超过20岁的男性和女性1958年-2011年进行了追踪随访。所有的参与者在1938年-1991年间出生,他们的成年身高范围在100-225cm。  

卡罗林斯卡医学院博士生Emelie Benyi博士领导了这项研究,他坚信,尽管既往有研究探索身高和民众患癌之间的关系,但这是第一次如此大规模探究身高与癌症之间关系的研究。 

参与人员的身高信息由瑞典医学出生登记中心、瑞典征兵登记中心和瑞典护照登记中心等处获得。参与人员的患癌信息由瑞典癌症登记中心获得。

研究人员发现,身高每增高10cm,女性罹患癌症的风险增加18%,男性增加11%,患黑色素瘤的风险男女性均增加约30%。此外,高挑的女性患乳腺癌的风险增加20%。 

既往研究中也印证了该观点。这就意味着,越高的人罹患不同癌症(包括黑色素瘤和乳腺癌)的风险也越大。

既往研究人员认为,这可能同早期的生命发展机制有关。原因之一可能是影响身高的环境因素,包括饮食和儿童时期发生的感染等可能也会起到一定的作用。另一个原因或许是机体的激素水平不同,尤其是与身高有关的激素(如胰岛素样生长因子)等有关。研究人员认为,IGF水平与民众罹患癌症的风险有关。此外,还有研究人员认为存在第三种原因,即高个子的人有更多的细胞(包括干细胞),这表明他们有更多的机会存在细胞恶变的机会。

Benyi博士认为,该研究结果反映了一定人口基数下民众的患癌发生率。当然需要进行更进一步的研究,以探究身高是否与某种特定癌症的发病率有莫大关联。但是高个子的人也不应恐慌,癌症的出现有多方面的原因,大家需要做的是规律饮食,健康生活。

此前,2011年一项研究也得出相似的结论。身高每增加10cm,总体癌症风险增加16%。

相关出处:

Green J, Cairns BJ, Casabonne D, Wright FL, Reeves G, Beral V; Million Women Study collaborators.Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer risk. Lancet Oncol. 2011 Aug;12(8):785-94.

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    2016-06-07 feather89
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    2016-05-26 shenxlcyp
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    2016-05-19 sjq027
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    2015-10-06 lq0307
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    2015-10-04 medcardio

    类姚明这样怎么办

    0

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